ST Elevation in a Patient With COVID-19 Infection-Associated Fever: A Case of Brugada Pattern

Mahadevaiah, Guruprasad; Aleem, Abdul; Secaira, Antonio; Saba, Samir; Shariff, Nasir

doi:10.7759/cureus.8722

Cited by 4 publications

(3 citation statements)

References 8 publications

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“…Mahadevaiah and colleagues have also described a 40-year-old patient with fever of 39.1 °C and chest pain, his ECG showing a type l Brugada pattern with normal troponin level and electrolytes [ 11 ] like our case.…”

Section: Discussionmentioning

confidence: 58%

Brugada Pattern: Unraveling Possible Cardiac Manifestation of SARS-CoV-2 Infection

Boncoraglio¹,

Esteves²,

Pereira³

et al. 2021

J Med Cases

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We report the case of a 41-year-old patient with no family history of sudden cardiac death. The patient presented with high fever and vomiting and was diagnosed with acute pyelonephritis. Screening for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was positive. An electrocardiogram (ECG) performed during a fever episode revealed a Brugada pattern. Fever can be a trigger for induction of the electrocardiographic Brugada pattern but it is still unknown if the cardiac involvement by coronavirus disease 2019 (COVID-19) can interfere with myocardial ion channels.

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Section: Discussionmentioning

confidence: 58%

Brugada Pattern: Unraveling Possible Cardiac Manifestation of SARS-CoV-2 Infection

Boncoraglio¹,

Esteves²,

Pereira³

et al. 2021

J Med Cases

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show abstract

“…In the literature, there are numerous case reports of adults with COVID‐19 who are found to have Brugada pattern or syndrome. 5 , 6 , 7 To our knowledge, there are only 2 published cases of COVID‐19 related Brugada pattern in pediatric patients. De Nigris et al described a 7‐year‐old who presented with 7 days of abdominal pain and fever, diagnosed with multisystem inflammatory syndrome in children with positive anti‐SARS‐COV‐2 immunoglobulin G antibodies at time of admission.…”

Section: Discussionmentioning

confidence: 99%

“…In the literature, there are numerous case reports of adults with COVID‐19 who are found to have Brugada pattern or syndrome 5–7 . To our knowledge, there are only 2 published cases of COVID‐19 related Brugada pattern in pediatric patients.…”

Section: Discussionmentioning

confidence: 99%

Brugada pattern in adolescent with acute myocarditis due to SARS‐CoV‐2

Bergamo¹,

Nelson²

2022

JACEP Open

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Brugada syndrome is a genetic disorder characterized by abnormal findings on electrocardiogram (ECG) that can precipitate ventricular tachyarrhythmias and sudden cardiac death. Most clinical manifestations of Brugada syndrome are related to life‐threatening tachyarrhythmias, such as ventricular fibrillation or polymorphic ventricular tachycardia, but Brugada syndrome can also present with syncope or less likely palpitations. Our case is of a previously healthy 17‐year‐old visiting from Puerto Rico who presented to the emergency department (ED) with a syncopal episode preceded by sore throat, dizziness, and lightheadedness without palpitations. The ED evaluation found a normal complete blood count and basic metabolic panel. The patient tested positive for COVID‐19 by polymerase chain reaction. An ECG was performed that showed the Brugada pattern, which was later confirmed by cardiology. Although Brugada syndrome and pattern are well known to the medical population, the findings of Brugada pattern in the setting of COVID‐19 is not well described. Recognition and treatment are important, as Brugada syndrome can lead to life‐threatening arrhythmias and sudden cardiac death.

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Getting to the Heart of the Matter: Myocardial Injury, Coagulopathy, and Other Potential Cardiovascular Implications of COVID-19

Schmid

Petrović

Akella

et al. 2021

International Journal of Vascular Medicine

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COVID-19 was primarily identified as a respiratory illness, but reports of patients presenting initially with cardiovascular complaints are rapidly emerging. Many patients also develop cardiovascular complications during and after COVID-19 infection. Underlying cardiovascular disease increases the severity of COVID-19 infection; however, it is unclear if COVID-19 increases the risk of or causes cardiovascular complications in patients without preexisting cardiovascular disease. The review is aimed at informing the primary care physicians of the potential cardiovascular complications, especially in patients without underlying cardiovascular disease. A comprehensive literature review was performed on cardiac and vascular complications of COVID-19. The primary cardiac and vascular complications include myocarditis, acute coronary syndrome, myocardial injury, arrhythmia, heart failure, shock, multisystem inflammatory syndrome, venous and arterial thrombotic events, stroke, and coagulopathy. A detailed analysis of the pathogenesis revealed six possible mechanisms: direct cardiac damage, hypoxia-induced injury, inflammation, a dysfunctional endothelial response, coagulopathy, and the catecholamine stress response. Autopsy reports from studies show cardiomegaly, hypertrophy, ventricular dilation, infarction, and fibrosis. A wide range of cardiac and vascular complications should be considered when treating patients with confirmed or suspected COVID-19 infection. Elevated troponin and natriuretic peptides indicate an early cardiac involvement in COVID-19. Continuous monitoring of coagulation by measuring serum D-dimer can potentially prevent vascular complications. A long-term screening protocol to follow-up the patients in the primary care settings is needed to follow-up with the patients who recovered from COVID cardiovascular complications.

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ST Elevation in a Patient With COVID-19 Infection-Associated Fever: A Case of Brugada Pattern

Cited by 4 publications

References 8 publications

Brugada Pattern: Unraveling Possible Cardiac Manifestation of SARS-CoV-2 Infection

Brugada Pattern: Unraveling Possible Cardiac Manifestation of SARS-CoV-2 Infection

Brugada pattern in adolescent with acute myocarditis due to SARS‐CoV‐2

Getting to the Heart of the Matter: Myocardial Injury, Coagulopathy, and Other Potential Cardiovascular Implications of COVID-19

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