ST-segment abnormalities and premature complexes are predictors of new-onset atrial fibrillation: The Niigata Preventive Medicine Study

Watanabe, Hiroshi; Tanabe, Naohito; Makiyama, Yashiro; Chopra, Sameer; Okura, Yuji; Sano, Hiroshi; Matsui, Kazumitsu; Watanabe, Tôru; Kurashina, Yoshiaki; Aizawa, Yoshifusa

doi:10.1016/j.ahj.2006.05.032

Cited by 49 publications

(40 citation statements)

References 19 publications

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“…We identified electrocardiographical evidence of myocardial ischaemia to be related to AF, in accordance to similar findings from the Renfrew/Paisley Study [23] and Niigata Preventive Medicine Study [25]. The presence of VPBs in the ECG, which was a significant AF risk factor in the Niigata Preventive Medicine Study, was independently associated with the presence of AF in our cohort.…”

Section: Discussionsupporting

confidence: 90%

Prevalence, clinical correlates and treatment of permanent atrial fibrillation among the elderly: insights from the first prospective population-based study in rural Greece

Ninios

Bogossian

Zarse

et al. 2009

J Thromb Thrombolysis

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To investigate the prevalence of permanent atrial fibrillation (AF), its clinical associated conditions and treatment status in the elderly population in rural Greece. 720 people (46.1% males) older than 65 years (mean age: 72.5 +/- 5.7 years) living in four villages in rural Greece were screened with an electrocardiogram (response rate: 90.5%) for the presence of permanent AF. They underwent a physical examination, including blood pressure (BP) measurement, and body mass index (BMI) calculation, in addition to an interview about their medical history, physical activity, smoking habits, alcohol consumption and medication use. Subjects with AF for whom anticoagulants were contraindicated were identified and stroke risk stratification was performed using the CHADS2 algorithm. The prevalence of permanent AF was 5% (6.6% among men and 3.6% among women) and it increased with age. In the entire population, ECG evidence of myocardial ischaemia and ventricular premature beats were independently associated with the presence of permanent AF (OR 5.266; 95% CI 2.22-12.49, P = 0.0001 and OR 2.61; 95% CI 1.059-6.432, P = 0.037, respectively), while female sex was independently associated with the absence of the AF (OR 0.327; CI 0.147-0.729, P = 0.006). From those patients who were eligible for anticoagulation, 40.6% were treated with anticoagulants, 34.3% were given antiplatelets therapy and the rest received no antithrombotic treatment. This is the first prospective study demonstrating the prevalence, clinical correlates and treatment status of permanent AF in Greece. These results confirm the high prevalence of permanent AF among the elderly and underscore the issue regarding anticoagulants underutilization.

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Section: Discussionsupporting

confidence: 90%

Prevalence, clinical correlates and treatment of permanent atrial fibrillation among the elderly: insights from the first prospective population-based study in rural Greece

Ninios

Bogossian

Zarse

et al. 2009

J Thromb Thrombolysis

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“…9 In the prefecture, annual health examinations supported by the administration are available to residents Ն20 years of age. The annual examination consists of a detailed medical history; physical examination; blood examination, including blood cell count and biochemical markers; chest x-ray; and a 12-lead ECG.…”

mentioning

confidence: 99%

Metabolic Syndrome and Risk of Development of Atrial Fibrillation

et al. 2008

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Background-The metabolic syndrome consists of a cluster of atherosclerotic risk factors, many of which also have been implicated in the genesis of atrial fibrillation (AF). However, the precise role of the metabolic syndrome in the development of AF is unknown. Methods and Results-This prospective, community-based, observational cohort study was based on an annual health check-up program in Japan. We studied 28 449 participants without baseline AF. We used 2 different criteria for the metabolic syndrome-the guidelines of the National Cholesterol Education Program Third Adult Treatment Panel (NCEP-ATP III) and those of the American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI)-to study the risk of development of new-onset AF. The metabolic syndrome was present in 3716 subjects (13%) and 4544 subjects (16%) using the NCEP-ATP III and AHA/NHLBI definitions, respectively. During a mean follow-up of 4.5 years, AF developed in 265 subjects (105 women

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“…PVCs have been associated with higher incidence of AF [61,62], HF [63] and ischemic stroke [61]. The association of PVCs with ischemic stroke was present even among apparently healthy individuals (nondiabetic, normotensive, without history of CHD or Q wave infracts) [61].…”

Section: Premature Ventricular Complexesmentioning

confidence: 98%

ECG abnormalities and stroke incidence

Agarwal¹,

Soliman

2013

Expert Review of Cardiovascular Therapy

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In this review, the authors discuss the role of ECG in prediction of stroke. ECG plays an important role in detection of several stroke risk factors/predictors including atrial fibrillation and left ventricular hypertrophy; both are components of the Framingham Stroke Risk Score. Multiple other ECG traits have also emerged as potential predictors of stroke, namely cardiac electrical/structural remodeling -Q wave, QRS/QT duration, bundle blocks, P wave duration/amplitude/dispersion, other waveform angles and slopes; higher automaticity -ectopic beats; and re-entry -atrial tachyarrhythmia; and higher vulnerability to arrhythmia -heart rate and its variability. Most of these predictors are not ready for prime time yet; however, further research focusing on their role in risk stratification and prevention of stroke may be useful. In this article, the authors discuss the prevalence, mechanisms and clinical applications of traditional and novel ECG markers in the prevention and treatment of stroke. ECG abnormalities and stroke incidenceExpert Rev. Cardiovasc. Ther. 11 (7), 853-861 (2013)

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ST-segment abnormalities and premature complexes are predictors of new-onset atrial fibrillation: The Niigata Preventive Medicine Study

Cited by 49 publications

References 19 publications

Prevalence, clinical correlates and treatment of permanent atrial fibrillation among the elderly: insights from the first prospective population-based study in rural Greece

Prevalence, clinical correlates and treatment of permanent atrial fibrillation among the elderly: insights from the first prospective population-based study in rural Greece

Metabolic Syndrome and Risk of Development of Atrial Fibrillation

ECG abnormalities and stroke incidence

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