a b s t r a c tThe nucleation and growth of helium (He) bubbles in the bulk and at R3h110i{1 1 2} and R73bh110i{6 6 1} grain boundaries (GBs) in bcc iron have been investigated using molecular dynamics simulations. The results show that a 1/2h1 1 1i{1 1 1} dislocation loop is formed with the sequential collection of h1 1 1i interstitial crowdions at the periphery of the He cluster and is eventually emitted from the He cluster. Insertion of 45 He atoms into a He cluster leads to the formation of a 1/2h1 1 1i dislocation loop in R3 GB. It is of interest to notice that the transition of a dislocation segment through the GB leads to the formation of a step at the GB plane following the loop formation, accounting for the formation of a residual GB defect. A 1/2h1 1 1i loop, with a {1 1 0} habit plane, is emitted with further increase of the He bubble size in the R3 GB. In contrast, the sequential insertion of He atoms in R73b GB continuously emits self-interstitial atoms (SIAs), but these SIAs rearrange at the core of the inherent GB dislocation, instead of forming a dislocation loop, which leads the GB dislocation to propagate along the ½ 1 1 1 2 direction. In the bulk and R3 GB, the He bubble exhibits three-dimensionally spherical shape, but it forms longitudinal shape along the dislocation line in the R73 GB, a shape commonly observed at GBs in experiments.