Compared with passenger cars, heavy vehicles have larger loads, longer bodies, more steering modes, and are more likely to cause improper steering angle relationships among the wheels, resulting in uncoordinated steering. This uncoordinated steering makes the tyres roll and drag, which results in abnormal lateral and longitudinal slips, changing the lateral and longitudinal mechanical characteristics of tyres and leading to low path tracking accuracy and poor steering performance of vehicles. Therefore, a tyre model containing lateral and longitudinal mechanical characteristics under heavy load is the key to solving the problem of uncoordinated steering in heavy vehicles. Firstly, with the physical tyre model, the lateral and longitudinal slip is described as carcass deflections. With the carcass deflections and contact pressure distribution of heavy load, the tyre forces under uncoordinated steering conditions are derived. Then, the tyre imprint parameters are obtained with a test bench, and a two-dimensional contact pressure distribution model is established to reproduce the contact pressure distribution of tyre under heavy loads and dynamic slips. The comparison results with Magic Formula (MF) and Trucksim are generally consistent, proving the effectiveness of the model. Finally, a lateral and longitudinal tyre force distribution control of vehicles is carried out based on the established model. The results of the Trucksim-Simulink co-simulation show that the path tracking accuracy of vehicles is significantly improved, which demonstrates that the tyre model incorporating lateral and longitudinal mechanical characteristics under heavy loads can provide a theoretical basis for solving the problem of uncoordinated steering in heavy vehicles.