Stability in Incidence of Acute Appendicitis

Kørner, Hartwig; Søreide, Jon Arne; Pedersen, Erik J.; Bru, Tore; Søndenaa, Karl; Vatten, Lars J.

doi:10.1159/000050099

Cited by 33 publications

(15 citation statements)

References 13 publications

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“…Reduced incidence of acute appendicitis in children was also reported by Aarabi and co‐workers6 in New England in 2000–2006. In contrast to these reports of declining rates, increased rates of appendicitis were reported from Norway8 and the USA10 11, and Livingston et al 9. identified a ‐shaped incidence rate trend, with increasing acute appendicitis rates in children in the USA up to 2004.…”

Section: Discussionmentioning

confidence: 93%

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Population-based cohort study on the epidemiology of acute appendicitis in children in Sweden in 1987-2013

et al. 2018

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BackgroundThe long‐term incidence of acute appendicitis has been reported to be declining in Europe and North America. Recent reports, however, indicate stabilized or even increased rates. The aim of this study was to investigate the present epidemiology of acute appendicitis and appendicectomy in a population‐based cohort of Swedish children.MethodsThe Swedish National Patient Register was queried for all children with acute appendicitis and/or appendicectomy in 1987–2013. Population‐based incidence rates were calculated. Rates were age‐ and sex‐adjusted, and analysed for temporal and regional trends.ResultsSome 56 774 children with acute appendicitis were identified, of whom 53 478 (94·2 per cent) underwent appendicectomy. The incidence rate of acute appendicitis declined by 43·7 per cent over 26 years, from 177·7 to 100·1 per 100 000 person‐years between 1987 and 2013. The most significant reduction was for non‐perforated appendicitis, from 138·5 to 68·4 per 100 000 person‐years between 1987 and 2009. The incidence rate of perforated appendicitis decreased from 28·0 to 19·9 per 100 000 person‐years and negative appendicectomies reduced from 48·5 to 3·6 per 100 000 person‐years during the study interval.ConclusionThe incidence rates of acute appendicitis and negative appendicectomy have reduced markedly in Swedish children over time, with significantly different trends amongst non‐perforated appendicitis and perforated appendicitis. The full explanation for the observed findings is unclear.

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Section: Discussionmentioning

confidence: 93%

“…Studies from Europe and North America report decreasing rates of acute appendicitis, both in general1, 2, 3, 4 and in children5 6. There have been, however, more recent reports of stabilized7 8 or even increased9, 10, 11 incidence rates during the first decade of the 21st century.…”

Section: Introductionmentioning

confidence: 99%

Population-based cohort study on the epidemiology of acute appendicitis in children in Sweden in 1987-2013

et al. 2018

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“…However, in the same study [12], the incidence of appendicitis was increasing and did not result in expected decreases in perforation rates. In another study, the incidence of acute appendicitis remained stable [13]. …”

Section: Discussionmentioning

confidence: 99%

Epidemiology of Appendectomy and Appendicitis in the Valencian Community (Spain), 1998–2007

et al. 2009

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Background/Aims: Our purpose was to study the incidence of appendectomy and appendicitis in the Valencian community (Spain) during a period of 10 years (1998–2007). Methods: Data on discharge diagnoses of appendectomy and appendicitis were downloaded from all public hospitals in the Valencian community. Results: We identified 44,683 cases of appendectomies and 42,742 cases of appendicitis (95.7%) during the study period. The age-standardized incidence rates among men ranked between 132.1 cases per 100,000 population in 2003 and 117.46 cases per 100,000 population in 2000 without a clear trend through the study period. The appendiceal perforation rate was 12.1% and the negative appendectomy rate 4.3%. The global mortality was 0.38%. Conclusions: The incidence of appendectomy in our community presents a slight descending trend. This decline is more intense in females. The appendix perforation rate is lower than in other studies. The death rate is similar to other studies; however, it is very low in patients of younger age.

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“…Acute appendicitis with 8.6 and 6.6% of prevalence among men and women, in turn, is a very common disease [1][2][3]. Generally, 7% of total population undergoes appendectomy [2].…”

Section: Introductionmentioning

confidence: 99%

The Effect of Local Tramadol Injection in Post Appendectomy Pain

Khazaei

Kalati

Borumand

et al. 2015

Zahedan J Res Med Sci

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Background: Tramadol is a weak synthetic opioid with an effective analgesic result. This medicine has both systemic and local anesthetic effects on peripheral nerve system. Objectives: The purpose of this study is to compare post-appendectomy analgesic effect of subcutaneous injection of tramadol with normal saline. Patients and Methods: This double blind study was conducted on 60 patients over 15 years old, who were randomly divided in two equal groups, i.e. tramadol and normal saline. After repairing fascia in appendectomy, 100 mg of tramadol that was diluted up to 10 mL and 10 mL normal saline were used for subcutaneously injection around the surgical wound in experimental and control groups, respectively. Then, the intensity of pain was recorded in the recovery room, and 6 and 24 hours after operation, based on NRS. In addition, number of petidine (with a dosage of 25 milligram) administered in the same period, in case of severe and moderate pain, was recorded. At the end, the intensity of pain during the mentioned time and the average use of petidine in two groups were compared. Results: The average of severe pain in recovery time (3.08 ± 1.44 versus 5.36 ± 2.02), 6 (3.36 ± 1.22 versus 5.36 ± 1.38) and 12 (2.08 ± 0.76 versus 3.08 ± 1.15) hours after operation was lower in tramadol group (P = 0.0001). Moreover, the amount of consumed petidine in the same period of time showed a clear reduction (P < 0.05). Conclusions: Subcutaneous injection of tramadol is an appropriate choice for reduction of post-appendectomy pain and decreasing need for potent narcotic painkillers. This treatment method can decrease side effects of using potent narcotics after appendectomy.

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Stability in Incidence of Acute Appendicitis

Cited by 33 publications

References 13 publications

Population-based cohort study on the epidemiology of acute appendicitis in children in Sweden in 1987-2013

Population-based cohort study on the epidemiology of acute appendicitis in children in Sweden in 1987-2013

Epidemiology of Appendectomy and Appendicitis in the Valencian Community (Spain), 1998–2007

The Effect of Local Tramadol Injection in Post Appendectomy Pain

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