Stability of blood carbon monoxide and hemoglobins during heating

Differential scanning microcalorimetry study of the thermal denaturation of haemoglobin

“…It has been reported that the melting point and decomposition temperature of powder Hb occurs at about 120 and 210 -C, respectively [1] whereas haemoglobin in water or buffer solutions shows a markedly lower unfolding temperatures ranging from 63 to 67 -C [2 -4]. Different aspects of haemoglobin stability are discussed in literature [1][2][3][4][5][6][7][8][9][10][11][12]. However there are relatively few papers dealing with studies of haemoglobin with the use of differential scanning calorimetry (DSC) measurements.…”

Using a “non uniform pulse sequence” can improve selective coagulation with a Nd:YAG laser (1.06 μm) thanks to Met‐hemoglobin absorption: A clinical study on blue leg veins

“…When considering a blood vessel, several studies have demonstrated that heating induces hemoglobin modification [5,6]. The change is due to oxidative reactions with formation of met-hemoglobin.…”

Assessment of carboxyhemoglobin, hydrogen cyanide and methemoglobin in fire victims: a novel approach

“…In an in vitro experiment, Seto [41] reported considerable changes in Hb forms and CO levels when blood samples were heated. MetHb was formed from Hb-O2 under mild heating, leading to the mistaken diagnosis of poisoning by oxidizable gases.…”