Stability of hydroxyprogesterone caproate alone and in a compounded pharmaceutical product

Zhao, Yang; Bettinger, Joseph; Caritis, Steve N.; Venkataramanan, Raman

doi:10.2146/ajhp130466

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Cited by 2 publications

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17-alpha hydroxyprogesterone caproate for preterm birth prevention: Where have we been, how did we get here, and where are we going?

Manuck

2017

Seminars in Perinatology

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Prematurity is a major public health problem in the United States and worldwide. Women with a history of a previous preterm birth are at high risk for recurrence. Progesterone is a key hormone involved in pregnancy maintenance. In general, progesterone is thought to maintain pregnancy through several closely linked mechanisms: (1) promotion of uterine quiescence, (2) inhibition of pro-inflammatory cells, and (3) immunosuppressive action. 17-Alpha hydroxyprogesterone caproate is currently the only medication approved to prevent recurrent preterm birth. The purpose of this review is to discuss the history of 17-alpha hydroxyprogesterone caproate use for recurrent preterm birth prevention, the rationale behind 17-alpha hydroxyprogesterone caproate administration, and current evidence-based indications for 17-alpha hydroxyprogesterone caproate use.

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17-alpha hydroxyprogesterone caproate for preterm birth prevention: Where have we been, how did we get here, and where are we going?

Manuck

2017

Seminars in Perinatology

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Halobetasol Propionate – Hydroxyzine Pamoate

2018

Trissel’s Stability of Compounded Formulations, 6e

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Stability of hydroxyprogesterone caproate alone and in a compounded pharmaceutical product

Abstract: Hydroxyprogesterone caproate in powder form and in a pharmaceutical formulation under different experimental conditions appeared to be fairly stable in the presence of strong acid, high temperatures, and light.

Cited by 2 publications

References 7 publications

17-alpha hydroxyprogesterone caproate for preterm birth prevention: Where have we been, how did we get here, and where are we going?

17-alpha hydroxyprogesterone caproate for preterm birth prevention: Where have we been, how did we get here, and where are we going?

Halobetasol Propionate – Hydroxyzine Pamoate

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