Stability of Radiomic Features to Multiple-Reader Segmentations in Contrast-Enhanced Computed Tomography (Cect) Images of Hepatocellular Carcinoma (Hcc)

Bettinelli, Andrea; Marturano, Francesca; Ballo, Mattia; Billato, Ilaria; Cabrelle, Giulio; Carandina, Riccardo; Crimì, Filippo; Lupi, Amalia; Paiusco, M.; Pizzirani, Enrico; Ricciardi, Costantino; Cillo, U.

doi:10.1016/s1120-1797(22)02227-x

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hepatitis B vaccination, antiviral treatment for hepatitis C, and lifestyle interventions to mitigate alcoholic liver disease or fatty liver are all routes to minimizing the risk of developing HCC. These strategies are not just preventive for HCC but are also essential for maintaining liver health, illustrating the interconnectedness of liver diseases and HCC [11].…”

Section: An Overview Of Hcc and Its Unique Challengesmentioning

confidence: 99%

Recent treatments to Hepatocellular Carcinoma Cancer(HCC): update and outlook

Lu,

2024

TNS

View full text Add to dashboard Cite

In the US, hepatocellular carcinoma (HCC), which accounts for 75%85% of instances of liver cancer, is a substantial cause of cancer-related fatalities. This review focuses on the recent developments in managing HCC, specifically through Trans-arterial Chemoembolization (TACE), which is currently first-line recommended and boasts a high survival rate. We have also discussed gene therapy, which aims to correct or replace faulty genes contributing to HCC development. Although it is still on trial, early results show promise. There are also various treatments such as OLT, molecularly targeted therapy, radiation therapy, locoregional therapies, gene therapy and immunotherapy. We have also come up with an innovative idea of creating a therapeutic vaccine using circRNA instead of mRNA, along with LNP, to treat HCC. This approach combines the benefits and functions of both circRNA and LNP. Different components of LNP aid in diverse benefits, to name but a few, stability, encapsulation and delivery efficiency, and higher targeting specificity. The use of circRNA offers adjuvant to immune response and better stability. Recent studies suggest that this hypothesis is theoretically possible. A better understanding of the hazardous disease could lead to the development of more effective treatments, which are urgently needed.

show abstract

Section: An Overview Of Hcc and Its Unique Challengesmentioning

confidence: 99%

Recent treatments to Hepatocellular Carcinoma Cancer(HCC): update and outlook

Lu,

2024

TNS

View full text Add to dashboard Cite

show abstract

Stability of Radiomic Features to Multiple-Reader Segmentations in Contrast-Enhanced Computed Tomography (Cect) Images of Hepatocellular Carcinoma (Hcc)

Cited by 1 publication

References 0 publications

Recent treatments to Hepatocellular Carcinoma Cancer(HCC): update and outlook

Recent treatments to Hepatocellular Carcinoma Cancer(HCC): update and outlook

Contact Info

Product

Resources

About