In this paper we study the onset of angiogenesis and derive a new model to describe it. This new model takes the form of a nonlocal Burgers equation with both diffusive and dispersive terms. For a particular value of the parameters, the equation reduces towhere H denotes the Hilber transform. In addition to the derivation of the new model, we also prove a number of well-posedness results. Finally, some preliminary numerics are shown. These numerics suggest that the dynamics of the equation is rich enough to have solutions that blow up in finite time.