Stability Studies of Phenylbutazone and Phenylbutazone-Antacid Oral Formulations

Quality Assessment of Solid Pharmaceuticals and Intravenous Fluid Manufacturing in Sub-Saharan Africa

“…The degradation products are shown in figure 1. Another work on influence of temperature on drugs was reported by Matsui et al, (1978) . It was observed that phenylbutazone (figure 3) formulations showed no evidence of chemical instability when stored at ambient temperature of 37°C.…”

Quality Control of Phenylbutazone I: Analysis of Phenylbutazone and Decomposition Products in Drugs by TLC

“…Empiric studies suggested preparation of the coating by mixing silica with pH 6 McIlvaine buffer (citric acid-dibasic sodium phosphate) (2), bismuth nitrate (13), or acid sodium sulfite (4).…”

Identification of Degradation Products in a Phenylbutazone Tablet Formulation

“…EXPERIMENTAL Materials-Tablets of Formulation G (1) were obtained directly from the manufacturer. These compounds are a-(N-phenylcarbamoy1)-N-caproylhydrazobenzene (I) and a-hydroxy-a-(N-phenylcarbam-oy1)-N-caproylhydrazobenzene (TI).…”