The coupled chemotaxis-fluid systemis considered under no-flux boundary conditions for n and c and no-slip boundary conditions for u in three-dimensional bounded domains with smooth boundary, where r ≥ 0 and μ > 0 are given constants and φ ∈ W 1,∞ (Ω) and g ∈ C 1 (Ω × [0, ∞)) ∩ L ∞ (Ω × (0, ∞)) are prescribed parameter functions. It is shown that under the explicit condition μ ≥ 23 and suitable regularity assumptions on the initial data, the corresponding initial-boundary problem possesses a global classical solution which is bounded. Apart from this, it is proved that if r = 0, then both n(·, t) and c(·, t) decay to zero with respect to the norm in L ∞ (Ω) as t → ∞, and that if, moreover, ∞ 0 Ω |g| 2 < ∞, then also u(·, t) → 0 in L ∞ (Ω) as t → ∞.Mathematics Subject Classification. 35K55 · 35Q92 · 35Q35 · 92C17.