Stabilization of a thermosetting emulsion system using ionic and nonionic surfactants

Polymer stabilisers for temperature-induced dispersion gelation: Versatility and control

“…The sticky microgel particles act as a "glue." Temperature-triggered gelation of latexes and emulsions has a number of potential applications which include controlled release [8] and glove-dipping. In the present work temperature-induced latex gelation using poly(NIPAM-co-PEGMa) is investigated for the first time in the presence and absence of added anionic surfactant.…”

Nonionic Cellulose Ethers as Potential Drug Delivery Systems for Periodontal Anesthesia

“…A synthetic membrane was used in this study because of the limited availability and reproducibility of mucosa derived from a suitable animal. Standard curves of the active ingredients were prepared for each drug diffusion experiment and used for calculation of the amount of prilocaine and lidocaine released in µmol/(cm 2 h) (13). The formulations were measured in duplicates and two samples of 5% (w/w) EMLA cream (containing 25 mg/g of lidocaine and prilocaine, respectively) and two samples of an EMLA cream formulation containing a total of 0.5% (w/w) active ingredients, with approximately the same viscosity as the 5% (w/w) formulation, were used as controls.…”

“…Before the measurements were started, all samples were left to equilibrate for 10 min. Oscillatory temperature sweeps were performed for some formulations according to a method described previously (13). All samples were measured in duplicates.…”

“…Using this approach, formulations with distinct and controllable in situ gelling could be combined with rapid release of the active components and excellent long-term stability (13,14). Considering the temperature-dependent thickening of at least some EHEC-surfactant solutions as well as the amphiphilic nature of some local anesthetic agents, we wanted to investigate mixtures of EHEC or HM-EHEC and surfactants in the presence and in the absence of active ingredients regarding their potential usefulness as local anesthetic formulations for the periodontal pocket.…”

Phase Transformations in Self‐Assembly Systems for Drug Delivery Applications

“…(Redrawn from Malmsten and Lindman[6] ) (b) Elastic modulus (G 0 ) for a 25 wt% Pluronic F127 solution versus temperature. (Redrawn from Scherlund et al[20] ) (c) Transition temperature for a mixture of Pluronic F127 and Pluronic F68 as a function of composition at a fixed total copolymer concentration of 21 wt%. (Redrawn from Scherlund et al[22] ) FIG.…”