1988
DOI: 10.1007/bf01569570
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Stabilization of anE. coli plasmid by a mini-F fragment of DNA

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Cited by 11 publications
(7 citation statements)
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“…Using a plasmid containing tryptophan synthase plus induction with 3-indole acrylate, recombinant E. coli was able to carry out a bioconversion producing 180 g l -1 of L-tryptophan from indole plus L-serine in 8 hours. 49 Production of L-phenylalanine amounted to 28 g l -1 when a plasmid was cloned into E. coli containing a feedback inhibitionresistant version of the CM-prephenate dehydratase (PD) gene, a feedback inhibition-resistant DAHPS and the O R P R and O L P L operator-promoter system of lambda phage. Control of plasmid expression was by temperature manipulation.…”
Section: Genome-wide Transcript Expression Analysis Riboflavinmentioning
confidence: 99%
“…Using a plasmid containing tryptophan synthase plus induction with 3-indole acrylate, recombinant E. coli was able to carry out a bioconversion producing 180 g l -1 of L-tryptophan from indole plus L-serine in 8 hours. 49 Production of L-phenylalanine amounted to 28 g l -1 when a plasmid was cloned into E. coli containing a feedback inhibitionresistant version of the CM-prephenate dehydratase (PD) gene, a feedback inhibition-resistant DAHPS and the O R P R and O L P L operator-promoter system of lambda phage. Control of plasmid expression was by temperature manipulation.…”
Section: Genome-wide Transcript Expression Analysis Riboflavinmentioning
confidence: 99%
“…Several genes which involve stabilization of plasmids were identified from naturally occurring plasmids such as mini F (Yukawa et al, 1988), R1 (Gerdes, 1988), and pSC101 (Meacock and Cohen, 1980), and applications of these genes to stabilize plasmids were reported (Skogman et al, 1983; Yukawa et al, 1988; Lee et al, 1994; Wu and Wood, 1994). These reports, however, dealt with expression of reporter genes or production of enzymes which are not toxic to host cells.…”
Section: Introductionmentioning
confidence: 99%
“…Recombinant DNA techniques have been useful in developing new bioconversions and improving old ones. Using a plasmid containing tryptophan synthase plus induction with 3‐indole acrylate, recombinant E. coli was able to produce 180 g L −1 of l ‐tryptophan from indole plus l ‐serine in 8 h (Yukawa et al , 1988). Whereas S. cerevisiae normally produces 2 g L −1 of malic acid from fumaric acid, a recombinant strain containing a cloned fumarase gene was able to produce 125 g L −1 with a yield of almost 90% (Neufeld et al , 1991).…”
Section: Improvement Of Microbial Processes By Genetic Engineeringmentioning
confidence: 99%