Stabilizer-free MnO2 nanozyme with singlet-oxygen conducted high oxidase-like activity and fast catalysis capability for improving alkaline phosphatase assay

Construct a Magnetic Pt/Ru Alloy Peroxidase Mimic As a Reusable and Cost-Effective “Signal-Off” Sensing Platform for Sensitive and Wide-Linear-Range Assay

“…By quantification of the resultant oxTMB concentration, which correlates with the absorbance signal, the analytes can be determined. So far, these sensing platforms have been widely used for the detection of AA, alkaline phosphatase (ALP), and acid phosphatase (ACP) . Despite the development of numerous OXD-based “signal-off” sensing platforms, there remains a critical need to enhance their performance in terms of lowering the limit of detection (LOD) and expanding the linear range (LR) to improve their clinical utility.…”