Stable Metal–Organic Frameworks for Fluorescent Detection of Tetracycline Antibiotics

Abstract

The rapid detection of antibiotics in agricultural products is of great significance. In this work, two stable fluorescent metal–organic frameworks (MOFs), BUT-178 and BUT-179, are synthesized and used to detect tetracycline antibiotics. Among them, BUT-179 exhibits better performance in the detection of different tetracycline antibiotics in water and eggs. The limits of detection of BUT-179 toward tetracycline, aureomycin, oxytetracycline, and doxycycline all reach the nanomolar level. Furthermore, the cycling tests confirm that BUT-179 can be easily recovered and repeatedly used without an obvious performance loss. This work demonstrates the excellent application potential of MOFs for food safety, especially the fluorescence detection of antibiotics in foods.

Detection Enhancement of One Multifunctional Cd-Metal–Organic Framework toward Tetracycline Antibiotics by Simply Mixing Eu3+ in Suspension

“…The detection limit values of LCU-117 toward OTC whether Eu 3+ was present or not are similar to those of recently reported samples (Table S4). − Time-dependent luminescence has been performed on the Eu 3+ @LCU-117 toward OTC (Figure c). Based on the result, all sensing activities showed fast response within 20 s. As far as we know, Ln 3+ post-modified MOF materials have generally been employed for chemisensors to detect antibiotics or other chemicals. ,− For example, very recently, He’s group reported one Eu 3+ -functionalized MOF named EuUCBA to detect TCs through luminescence quenching, which showed a low detection limit of 0.118 μM toward OTC .…”

Metal–organic framework (MOF)-based fluorescence “turn-on” sensors

“…[121][122][123] With the increase in the population globally, the intake of antibiotics has significantly increased, which has a negative effect on the environment. 124 Also, the side effects associated with antibiotics negatively impact human health and cause several diseases. 125,126 More importantly, taking antibiotics a for longer time will result in the development of antibiotic resistance in the body, which is fatal.…”

A Zn(II)–Metal–Organic Framework Based on 4-(4-Carboxy phenoxy) Phthalate Acid as Luminescent Sensor for Detection of Acetone and Tetracycline

“…However, TC is not fully absorbed during animal metabolism and enters the environment with feces. Hence, large amounts of TC residues are often found in soil and water environments [ 4 , 5 , 6 ]. In addition, acetone is a typical volatile organic solvent widely used in cosmetics, adhesives, and other commercial products.…”