Stable Suspension of Erythrocytes Suitable for Calibration of the Electronic Counters

Torlontano, G; Tata, A.N.

doi:10.1159/000208643

Cited by 3 publications

(1 citation statement)

References 4 publications

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“…Native white cells may be replaced in a stabilised whole blood preparation by either inert particles, fixed human red cells, or fixed avian cells (Lappin and Sanderson, 1970;Lewis, 1972b;Torlontano and Tata, 1972).…”

Section: Whole Blood Controlmentioning

confidence: 99%

A whole blood control for the Coulter Model S.

Morgan¹,

Jones²,

Fisher³

et al. 1978

J Clin Pathol

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SUMMARY The white cell count, red cell count, haemoglobin, and mean cell volume of a new preserved whole blood preparation used as a control material for the Coulter Model S were found to be stable for at least two months. This material provides a cheap and stable whole blood control which is now in routine use in 18 laboratories throughout Wales.Quality control of automated blood counting systems is an essential part of the activity of a haematology laboratory. Effective quality control requires the inclusion of control samples in the routine test procedure (Brittin et al., 1969;Overton, 1971;Cavill and Jacobs, 1973) and analysis of the data by statistical methods. A simple and effective method for statistical analysis of control data has been developed (Cavill and Ricketts, 1974). Application of it has been limited by lack of a suitable control preparation. Existing commercial preparations are expensive and their supply is never assured.A number of methods have been developed for stabilising blood by fixation. These have been reviewed by Lewis (1975), who concluded that fixed cells were more useful as standards for instrument calibration than for intralaboratory quality control. We have evaluated a new preparation containing fixed and partly fixed cells to see whether blood cells treated in this way could be used for the control of automated blood counters.

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Section: Whole Blood Controlmentioning

confidence: 99%