Stage I (t1 N0 M0) squamous cell carcinoma of the laryngeal glottis: Therapeutic results and voice preservation

Spector, J. Gershon; Sessions, Donald G.; Chao, K. A.; Haughey, Bruce H.; Hanson, Jason M.; Simpson, J.R.; Perez, Cherie

doi:10.1002/(sici)1097-0347(199912)21:8<707::aid-hed5>3.3.co;2-u

“…Early glottic cancer-specific (tumour stage one or two) has an excellent prognosis, with five-year cancer specific survival rates of 85-95 per cent. 15,16 The conservative treatment modalities used in early stage glottic cancer, namely radiotherapy and endoscopic laser surgery, are equivalent in terms of local control. 17,18 However, reports comparing the quality of voice after both treatments vary in their findings; some report a better voice following radiotherapy, 19,20 while others report no difference.…”

Section: Introductionmentioning

confidence: 99%

Electroglottogram approximate entropy: a novel single parameter for objective voice assessment

Douglas

¹

,

Moore

²

,

Manickam

³

et al. 2010

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“…The local control rates were 94% and ultimate local control was achieved in 66 patients (99%), and 65 patients (97%) experienced laryngeal preservation. Spector in 1999, 11 reported 404 patients of T1 glottic cancer with a local control rate of 92% and laryngeal preservation rate of 93% and achieving ultimate local control of 99%. In another study Spector,12 reported 71 patients of T2 glottic cancer with a local control of 93% and laryngeal preservation in 93% and ultimate local control of 99%.…”

Section: Management Of T1 and T2 Glottic Cancermentioning

confidence: 99%

Comparision of Transoral Laser and Open Partial Laryngectomy for T1 and T2 Glottic Cancer: A Review of literature.

Singh

¹

2012

Int J of Biomed & Adv Res

0

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T1-T2 glottic carcinomas may be treated with conservative surgery or radiotherapy. The goals of treatment are cure and laryngeal voice preservation. The aim of the current study was to review the literature and discuss the optimal management of T1 and T2 glottic carcinoma. Literature review indicated that the local control, laryngeal preservation, and survival rates of patients were similar after transoral laser resection and open partial laryngectomy. Voice quality depended on the extent of resection for patients undergoing surgery; results for patients undergoing laser resection for limited lesions showed better Voice Handicap Index scores, whereas open partial laryngectomy yielded poorer results. The cost of treatment was more for open partial laryngectomy. Patients with well defined lesions suitable for transoral laser excision with a good functional outcome were treated with laser. Open partial laryngectomy was reserved for patients with locally recurrent tumors. This review has been conducted by analyzing the Data which has been displayed in Pubmed literature in the last 25 years on the topics of Transoral Laser and Open partial Laryngectomy in the management of T1 and T2 glottic cancer. The various original articles and review articles were analyzed and compared and a conclusion derived.

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“…Both modalities have high local control, larynx preservation and high diseasespecific survival rates, and all retrospective data available in the literature show that these two treatment modalities are comparable for T1a glottic cancer. However, no randomized trial has been performed and the choice of the treatment is often based on the local expertise and/or patient preference [8,14,23,39,40,42,46,54].…”

Section: Introductionmentioning

confidence: 99%

“…Both modalities have high local control, larynx preservation and high diseasespecific survival rates, and all retrospective data available in the literature show that these two treatment modalities are comparable for T1a glottic cancer. However, no randomized trial has been performed and the choice of the treatment is often based on the local expertise and/or patient preference [8,14,23,39,40,42,46,54].Over the last decade, functional outcome and voice quality seem to play a key role in the treatment strategies. In fact, radiotherapy is often preferred because it seems to be associated with reduced impairment of voice quality, but qualitative studies about vocal function in post-irradiated patients have been inconclusive and not uniform [12,16,17,18,20,28,31,48,50].…”

mentioning

confidence: 99%