Staged Laparoscopic Infusion of Hyperthermic Intraperitoneal Chemotherapy After Cytoreductive Surgery

B ultrasound-guided hyperthermic intraperitoneal perfusion chemotherapy for the treatment of malignant ascites

“…Admittedly, laparoscopy has an advantage of detecting occult peritoneal carcinomatosis over B ultrasound, CT, MRI or PET-CT for evaluation of the stage of peritoneal malignant tumor in order to avoid any unnecessary surgery (1,13,15,18,19,28). Therefore, for those patients with unknown primary lesion status of peritoneal cancer without surgical operation, especially with ovarian cancer, an exploratory laparotomy should be performed as soon as possible after the CHIPC together with new adjuvant chemotherapy for a better prognosis.…”

Staged laparoscopic adjuvant intraperitoneal chemohyperthermia after complete resection for locally advanced colorectal or gastric cancer: a preliminary experience

“…Only a few studies have used laparoscopy to perform IPCH [38,39]. A pilot study of seven patients treated with laparoscopic IPCH was reported by Chang et al [39] from the National Cancer Institute.…”

“…The remaining two patients had intractable ascites from peritoneal metastases and underwent laparoscopic IPCH without cytoreductive surgery. Knusten et al [38] reported five patients who had staged laparoscopic infusion of IPCH after open cytoreductive surgery.…”

Palliative Treatments

“…Onset of MA affects QoL and carries poor prognosis. Most symptoms reported are due to progressive abdominal distension that causes abdominal pain, dyspnea, anorexia, hemorrhagic complications, bowel obstruction, and systemic disorders such as protein depletion and hydroelectrolyte disorders [15,16]. Standard treatments include salt-restricted diets, diuretics, repeated paracentesis, permanent drains, and peritoneal venous shunts in resistant cases [17].…”