Staining the Chromosomes of Yeast by the Feulgen Technique

Subramaniam, M. K.; Ranganathan, B.

doi:10.1038/157657a0

Cited by 6 publications

(1 citation statement)

References 5 publications

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“…While auxotrophic mutants were generated in Allomyces , genetics were complicated by the alternation of generations and tendency to generate autotetraploids. In keeping with progress in diverse research areas, fungal chromosome were targeted for analysis early in the classical genetics era (Subramaniam & Ranganathan 1946) and revealed a similarity between bacterial and fungal chromosomes (Lindegren 1948) ultimately leading to characterisation of fungal karyotypes in Sordaria (Carr & Olive 1958) and Ceratocystis (Aist 1969). Fungal model organisms soon came to the attention of classical cytologists and led to the observation of Neurospora (McClintock 1945) and Aspergillus (Elliott 1960) chromosomes.…”

Section: Introductionmentioning

confidence: 99%

Diverse data supports the transition of filamentous fungal model organisms into the post-genomics era

McCluskey

Baker

2017

Mycology

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Filamentous fungi have been important as model organisms since the beginning of modern biological inquiry and have benefitted from open data since the earliest genetic maps were shared. From early origins in simple Mendelian genetics of mating types, parasexual genetics of colony colour, and the foundational demonstration of the segregation of a nutritional requirement, the contribution of research systems utilising filamentous fungi has spanned the biochemical genetics era, through the molecular genetics era, and now are at the very foundation of diverse omics approaches to research and development. Fungal model organisms have come from most major taxonomic groups although Ascomycete filamentous fungi have seen the most major sustained effort. In addition to the published material about filamentous fungi, shared molecular tools have found application in every area of fungal biology. Similarly, shared data has contributed to the success of model systems. The scale of data supporting research with filamentous fungi has grown by 10 to 12 orders of magnitude. From genetic to molecular maps, expression databases, and finally genome resources, the open and collaborative nature of the research communities has assured that the rising tide of data has lifted all of the research systems together.

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