Adopting a scoping review method, we examined peer‐reviewed academic papers published about human–lion conflict (HLC) (including coexistence) and identified knowledge gaps. We searched papers published between January 1981 and December 2023 using academic databases, with the key terms African lion, human–lion conflict, human–lion coexistence, and human–lion interaction. This produced 485 records, reduced to 137 after using additional criteria. Ninety‐eight papers were focused on lions in Kenya, Tanzania, Zimbabwe, and Botswana. Ten pan‐African studies were identified in our review. Our inductive analysis identified four themes related to HLC: attitudes and perceptions toward lions, causes of HLC, consequences of HLC, and mitigating HLC. Some limitations identified in systematic reviews of human–wildlife conflict have been addressed in recent years, such as broadening the geographical scale of research. However, some knowledge gaps remain, including a lack of assessment of mitigation strategies and studies on climate changes impact on human–lion conflict. Addressing the knowledge gaps highlighted in this review will require diversifying the disciplinary composition of the research teams and increasing researcher reflexivity.