Stalagmite-like pre-retinal deposits in the optical coherence tomography of two vitrectomy patients with panuveitis

Monar, P.S. Calles; Ruiz-Colmenares, M.R. Sanabria; Suárez, M.T. Cano; Arriba, S. García de; Tarancón, A.M. Alonso; Díaz, S. Villoria

doi:10.1016/j.oftale.2020.12.015

Cited by 2 publications

(2 citation statements)

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“…Paulus et al reported the pathologic and cytologic findings of preretinal condensations in two patients with chronic uveitis, revealing the only presence of inflammatory cells ( 17 ). Calles Monar et al believed the white cells could migrate through the retinal vessels into the vitreous and proposed that the deposits described in the avascular fovea are similar to precipitates in the corneal endothelium ( 9 ). However, in our patient, the PDs seem not to be from the retinal vessels but the VC.…”

Section: Discussionmentioning

confidence: 99%

“…These PDs resolved in a few weeks spontaneously or in response to corticosteroids together with anterior uveal inflammation (4). Subsequently, PDs were increasingly reported in different diseases, including infectious diseases [ocular toxoplasmosis (OT) (5)(6)(7)(8)(9)(10)(11), syphilitic uveitis (12)(13)(14)(15)(16), vitreoretinal lymphoma (VRL) (8,(17)(18)(19)(20), HAU or HTLV-I carriers (4,21) and acute retinal necrosis (ARN) (22,23), and endogenous fungal endophthalmites] (24-28), and uveitis without a certain etiology (9,17). In some iatrogenic conditions, exogenous materials comprising silicone oil (SO) tamponade (29)(30)(31)(32)(33), intravitreal antibiotics (34,35), and the suspicious vitreous remnant of a viscoelastic substance (36) can also present with PDs.…”

Section: Introductionmentioning

confidence: 99%

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Case report: A rare appearance of preretinal deposits in a patient with uveitis: multimodal imaging observation

Cheng,

Chen,

Xiao

et al. 2023

Front. Med.

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BackgroundUveitis is a disease presenting with varied clinical symptoms and potentially devastates visual function. Here, we report a patient with uveitis exhibiting a rare appearance of preretinal deposits (PDs).Case presentationA 49-year-old female showed vitreous opacity and perivascular white PDs involving veins and arteries. The interferon-gamma release assay was strongly positive and chest computed tomography showed signs of calcified nodules; other tests were unremarkable. The patient was diagnosed with uveitis and tubercular infection. The patient was given systemic anti-tubercular therapy and steroids, which were subsequently combined with immunosuppressants. The shrinkage of HRD was more sensitively observed with OCT than on photographs during follow-up visits. The right eye was relieved subsequently, but the left eye showed vitreous opacity and responded poorly to the treatment. Three months after the dexamethasone intravitreal implant, the perivascular deposits in the left eye disappeared and the vitreous opacity was relieved.ConclusionPDs can appear as spotted deposits in the posterior pole and segmental deposits in the periphery in patients with uveitis, which mainly involves the vitreous cavity and is easily confused with retinal vasculitis. OCT can more sensitively observe the response than other examinations.

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Section: Discussionmentioning

confidence: 99%