This study entailed a load evaluation for the tower design of a large floating offshore wind turbine system in accordance with the wave conditions. The target model includes the IEA 15 MW reference wind turbine and a semi-submersible VolturnUS-S reference floating offshore wind turbine platform from the University of Maine. The OpenFAST, which is an aero-hydro-servo-elastic fully coupled analysis tool, was used for load analysis. The DLC1.2 and 1.6 were used as the design load cases, and the environmental conditions suitable for the design load cases were cited in the VolturnUS-S platform report. Load evaluation was performed according to time series and FFT results. The findings of the study are as follows: first, in the correlation analysis, the tower-top deflection had the highest correlation, and this further affects nacelle acceleration. Second, the tower-base pitch moment increased with the significant wave height. However, the wave peak period increased until it matched the tower-top deflection frequency and decreased thereafter. Third, the comparison between the normal and severe sea state conditions revealed that the tower-base pitch moments for the two conditions are almost similar, despite the conditions wherein the wave spectral energy differs by a factor of 3.5. Fourth, the tower shape is changed while adjusting the diameter of the tower, and the tower-top and tower-base pitch moments are reviewed using a redesigned tower. Even if the mass is the same, adjusting the diameter of the tower reduces only the pitch moment.