Standard molar enthalpy of formation of [(C12H8N2)2Bi(O2NO)3] and its biological activity on Schizosaccharomyces pombe

Li, Chuanhua; Jiang, Yong; Jiang, Jian‐Hong; Xu, Li; Xiao, Sheng-Xiong; Tao, Liming; Yao, Fei-Hong; Zhang, Hui; Yao, Long-Hua; Zhou, Hua; Xiang, Ying-Hui; Tian, Yongtao; Li, Qiang‐Guo

doi:10.1007/s10973-017-6104-z

Cited by 7 publications

(3 citation statements)

References 19 publications

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“…As the thermal properties of new compounds often limit the practical applicability [27][28][29][30][31][32][33], the ligands and the corresponding zinc(II) complexes were thermally characterized. In Figure 4 The sharp endothermic peaks on the DSC curves refer to the melting of the ligands ( Figure 5) The melting peak (t peak =245.6 o C) of HzDPK is immediately followed by its decomposition (t peak = 283.8 o C).…”

Section: Thermal Analysis Simultaneous Tg -Dsc Measurementsmentioning

confidence: 99%

Synthesis and characterization of diazine-ring containing hydrazones and their Zn(II) complexes

Magyari

Holló

Rodić

et al. 2017

J Therm Anal Calorim

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Two new zinc(II) coordination compounds have been synthesized by the reaction of diazine-ring containing Schiff bases di(2-pyridyl) ketone phthalazine-1-hydrazone (HzDPK) and di(2-pyridyl) ketone 3chloropyridazine-6-hydrazone (HpDPK) with zinc(II) salts in acetonitrile in the presence of triethylamine. The crystal and molecular structures of the complexes and that of the ligand HpDPK were determined by singlecrystal X-ray structure analysis. In both complexes, zinc atoms are situated in distorted octahedral environments, formed by two meridionally coordinated NNN tridentate, mono-deprotonated ligands. Since the applicability of the coordination compounds depends on their thermal properties, the thermal decomposition of the ligands and their complexes was followed by simultaneous TG-DSC measurements. The desolvation process of the complexes is rather slow as a consequence of a restricted diffusion through the lattice and finishes ~ 200 ˚C. The desolvated compounds are stable up to 340 ˚C. In order to follow the solvent evaporation and to have a better insight into the decomposition mechanism of the compounds coupled TG-MS measurements were carried out.

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Section: Thermal Analysis Simultaneous Tg -Dsc Measurementsmentioning

confidence: 99%

Synthesis and characterization of diazine-ring containing hydrazones and their Zn(II) complexes

Magyari

Holló

Rodić

et al. 2017

J Therm Anal Calorim

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“…Then, Schiff base and its bismuth(III) complex were evaluated in vitro for their antimicrobial and anticancer activities. As a part of our ongoing studies, [ 24–29 ] the aim of this work is to provide some valuable information for the development of some high‐efficiency, low‐toxicity antibacterial and antitumor drugs.…”

Section: Introductionmentioning

confidence: 99%

Dinuclear bismuth(III) complex constructed by isoniazid‐derived Schiff base: Synthesis, crystal structure, and biological activity

Li¹,

Ji²,

Zhang³

et al. 2022

Applied Organom Chemis

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A new bismuth(III) Schiff-base complex [Bi 2 (HL) 2 (NO 3 ) 4 (CH 3 OH)]•2CH 3 OH was prepared by reaction of the equivalent molar of Schiff-base ligandand Bi (NO 3 ) 3 •5H 2 O with the assistance of mannitol. The complex was structurally characterized by elemental analysis, spectroscopic methods (FT-IR, MS, 1 HNMR, and 13 CNMR) and single crystal X-ray diffraction. The molecular structure of the complex reveals that the ligand forms a 1:1 complex with bismuth(III) ion. It is composed of two 7-coordinated bismuth(III) ions, two tetradentate O 2 N-donor ligands, four nitrate ions, and three methanol molecules. The complex and its free ligand were evaluated against gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis) and gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa). The complex was more active than the ligand against all bacterial strains. Their cytotoxic activity was also investigated against SNU-16 cell. The complex is approximately three times more potent than the ligand, with the IC 50 values 0.35 and 1.18 μM for the complex and its ligand, respectively.

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“…However, Schiff base was re‐decomposed into 2‐aminobenzothiazole, followed by reaction with silver(I) ion to form the title complex. As a part of our continuing studies, [ 27–31 ] we have first performed the density functional theory (DFT) calculations of the complex. Subsequently, the inhibitory effect of the complex was tested by bio‐microcalorimetry on the growth of Schizosaccharomyces pombe .…”

Section: Introductionmentioning

confidence: 99%

Synthesis, crystal structure, density functional theory calculations, and antimicrobial activity of silver(I) complex derived from 2‐aminobenzothiazole ligand

Jiang

Lei

et al. 2021

Applied Organom Chemis

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Reaction of silver nitrate with 2‐aminobenzothiazole (abbreviated as Habt) in methanol at 45°C gave mononuclear complex of formula [Ag (Habt)2]NO3•CH3OH. The structure of the complex was characterized by infrared (IR) spectra, single crystal X‐ray diffraction, and elemental analysis. X‐ray diffraction analysis indicated that the title complex was crystallized in the triclinic crystal system with space group P–1, in which silver(I) ion was coordinated to two 2‐aminobenzothiazole ligands through the benzothiazol nitrogen atom. Theoretical study of the complex was carried out by density functional theory (DFT) B3LYP method. The antimicrobial effects of the ligand and its silver(I) complex were evaluated by bio‐microcalorimetry on the growth of Schizosaccharomyces pombe (S. pombe). Some quantitative metabolic parameters, such as growth rate constant (k), maximum heat power (Pmax), inhibition ratio (I), and half inhibition concentration (IC50), were derived from the metabolic power–time curves of S. pombe growth. The half inhibition concentration (IC50) of the ligand was calculated to be 2.58 × 10−3 mol L−1. The complex could strongly influence the lag phase of S. pombe.

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Standard molar enthalpy of formation of [(C12H8N2)2Bi(O2NO)3] and its biological activity on Schizosaccharomyces pombe

Cited by 7 publications

References 19 publications

Synthesis and characterization of diazine-ring containing hydrazones and their Zn(II) complexes

Synthesis and characterization of diazine-ring containing hydrazones and their Zn(II) complexes

Dinuclear bismuth(III) complex constructed by isoniazid‐derived Schiff base: Synthesis, crystal structure, and biological activity

Synthesis, crystal structure, density functional theory calculations, and antimicrobial activity of silver(I) complex derived from 2‐aminobenzothiazole ligand

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