Standardization of adventitious root induction in stem cuttings of Cynometra travancorica Bedd Willd., an endangered tree species of Western Ghats

Hrideek, T. K.; Geethu, P.D.; Jijeesh, C. M.; Raghu, A. V.; Muraleekrishnan, K.

doi:10.1007/s42535-019-00002-x

Cited by 4 publications

(1 citation statement)

References 11 publications

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“…It is typical to employ replacements from other plants of Caesalpiniaceae species, especially Cynometra travancorica (C. travancorica). The botanical wealth of secondary metabolites found in the genus Cynometra has been linked to the biological functions and therapeutic applications mentioned for the medicinal plants incorporating it [27]. Uncertainty exists regarding the medicinal potential of C. travancorica.…”

Section: Introductionmentioning

confidence: 99%

Comparative evaluation of anti-obesity effect through pancreatic lipase inhibition of methanolic extract of the bark of Saraca asoca and Cynometra travancorica

SUHAIL,

CHRISTAPHER,

JOSEPH

et al. 2023

jrp

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Saraca Asoca, a member of the Caesalpiniaceae sub-family, is a native plant utilized extensively in ayurvedic medicine. This study compares the anti-obesity effect of methanolic extract of the bark of Saraca asoca and Cynometra travancorica, two common ingredients of many Indian traditional medicines. Plant material extracts were prepared using simple maceration technique. Adult 150-180 gm weighed Sprague dawley rats were used for high fat diet induced in vivo anti-obesity study for eight weeks. Weekly bodyweight was measured, and terminal serum lipid profile was estimated to assess the anti-obesity activity of standard drug orlistat (60 mg/kg) and extracts at a dose of 400 mg/kg. In vitro enzyme inhibition study was performed to assess the effect of standard or extracts on pancreatic lipase. Increase in bodyweight found corresponding with the normal weight gain for the control group whereas it is significantly increased with high fat diet fed group. While in the orlistat or extract treated found to have resisted significant changes in bodyweight (p<0.001). Terminal blood samples were collected from all animals and serum lipid profile were evaluated. An increase in the levels of TC, TG, and LDL of animals in high fat diet fed group when compared to normal control group. Whereas the increase lipid levels were reversed in all treated groups. HDL level found to have increased in standard and extract treated groups. In vitro enzyme inhibition study revealed the inhibitory potential of S. asoka (IC50 of 306.15µg/ml) and C. travancorica (IC50 of 301.94 µg/ml) on pancreatic lipase when compared with orlistat (IC50 of 262.17 µg/ml) (p<0.05). This study suggests that the methanolic extract of the bark of S. asoca and C. travancorica possess significant anti-obesity activity on high fat diet induced obesity rat model and in-vitro pancreatic lipase inhibition.

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Section: Introductionmentioning

confidence: 99%

Comparative evaluation of anti-obesity effect through pancreatic lipase inhibition of methanolic extract of the bark of Saraca asoca and Cynometra travancorica

SUHAIL,

CHRISTAPHER,

JOSEPH

et al. 2023

jrp

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TDZ induced plant regeneration from immature cotyledons of Pterocarpus marsupium Roxb. and validation of genetic homogeneity using ISSR markers

Tippani

Thammidala

2021

Vegetos

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Amelioration of sodium fluoride induced oxidative stress by Cynometra travancorica Bedd in mice

Meera

Divya

Srinivasu

et al. 2021

Journal of Complementary and Integrative Medicine

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Objectives Cynometra travancorica, endemic to Western Ghats of India is pharmacologically similar to Saraca asoca and occasionally used as substitute in a well-known Ayurvedic uterine tonic Asokarishta. S. asoca possess various biological properties, but there are no reports on C. travancorica. The present study evaluated the pharmacological properties of C. travancorica and its efficacy in attenuating the sodium fluoride (NaF) induced oxidative stress in mice. Methods Antioxidant potential of methanolic extract of C. travancorica (CTE) stem bark was evaluated using DPPH, superoxide radical scavenging and total antioxidant assays. The effect of CTE on mitigating NaF deteriorated redox status in the liver tissue of mice was evaluated. Functional groups in CTE were analyzed by FTIR analysis. Results CTE effectively scavenged the free radicals in in vitro condition. CTE could augment catalase (46.6%), superoxide dismutase (53.8%) activities and GSH level (48.1%) against NaF induced decline in the liver tissue of mice. The peroxidation of lipids was found to be decreased by 44.9% and tissue damage abated as inferred by histopathology. FTIR analysis revealed the presence of biologically active functional groups in CTE. Conclusions The study revealed the ameliorative effect of C. travancorica against NaF induced deleterious effect in experimental animals by its potent antioxidant potential.

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Standardization of adventitious root induction in stem cuttings of Cynometra travancorica Bedd Willd., an endangered tree species of Western Ghats

Cited by 4 publications

References 11 publications

Comparative evaluation of anti-obesity effect through pancreatic lipase inhibition of methanolic extract of the bark of Saraca asoca and Cynometra travancorica

Comparative evaluation of anti-obesity effect through pancreatic lipase inhibition of methanolic extract of the bark of Saraca asoca and Cynometra travancorica

TDZ induced plant regeneration from immature cotyledons of Pterocarpus marsupium Roxb. and validation of genetic homogeneity using ISSR markers

Amelioration of sodium fluoride induced oxidative stress by Cynometra travancorica Bedd in mice

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