Standardization of Vellarugu Chooranam: A Siddha Herbal Drug

Sanmugarajah, Vinotha; Thabrew, Ira; Sivapalan, Sri Ranjani

doi:10.47070/ijapr.v2i3.242

Cited by 2 publications

(3 citation statements)

References 4 publications

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“…So, while developing an herbal drug formulation it is must to have the related knowledge of that particular drug including all its organoleptic characters to phyto-constituents to pharmacological action to its standardization in respect to various parameters via various techniques. 4 Standardization need for Global acceptance, documentation, reproducibility, industrial scale production, prevent adulteration and contamination, assess the quality of raw material and finished product, estimate the amount of active principle, achieve batch to batch consistency of finished product. 15…”

Section: Resultsmentioning

confidence: 99%

“…3 Drug Standardization is an essential factor for herbal formulation in order to assess the quality of the drugs based on the concentration of their active principle and to ensure that every packet of medicine that is sold has the correct amount and will induce its therapeutic action. 4 In this study the parameters for quality assessment have been followed as per CCRAS guidelines for Analytical specifications of Chooranam. 5 were carried out by using ICP MS and HPLC FLD as per the procedure WHO Q AS/05-131 and AOAC 990.33.…”

Section: Introductionmentioning

confidence: 99%

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Standardization of a Siddha Poly Herbal Formulation Adhathodai Chooranam

H¹,

Manickavasakam²,

Mohan³

2015

Int. J. Res. Ayurveda Pharm.

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Siddha Drugs are natural products obtained from herbs, metals, minerals and animal kingdom. With the growing awareness of health care and safety aspects, people are moving towards herbal products. Proper standardization of drug preparation method as well as chemical analysis of traditional formulation is mandatory to gain support for its use worldwide. Aadhathodai chooranum is a siddha sastric drug for the treatment of Bronchial Asthma. Literature review evidenced no standardization work so far. The present study was carried out to standardize Aadhathodai Chooranam by evaluating its organoleptic properties, preliminary phyto chemical screening, physico chemical analysis, Thin Layer Chromatography (TLC), High Performance Thin Layer Chromatography (HPTLC) finger print, heavy metal analysis, Microbial load and Aflatoxin content for further application in clinical trial of bronchial Asthma. The loss on drying at 105°C, Ash, Acid insoluble Ash, Water soluble extractive, Alcohol soluble extractive and pH of Aadathodai Chooranam were 11.16%.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Standardization of a Siddha Poly Herbal Formulation Adhathodai Chooranam

H¹,

Manickavasakam²,

Mohan³

2015

Int. J. Res. Ayurveda Pharm.

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show abstract

“…"Standardization is an essential factor for herbal formulation in order to assess the quality of the drug based on the concentration of their active principle and to ensure that every packet of medicine that is sold has the correct amount and will induce its therapeutic effect" [3].…”

Section: Introductionmentioning

confidence: 99%

Standardization of Gowthamar chooranam – A Polyherbal Siddha Formulations in the Management of Swasakasam (Bronchial Asthma)

Anitha Kalaivani M.,

Shamshalniha S.,

Anbu N.

2023

J. Pharm. Res. Int.

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Background: Siddha medicine is a unique one as it is not only a curative but also preventive and to achieve the healthy body and mind. Siddha medicines revitalize and rejuvenate the body. Bronchial asthma, characterized by chronic airway obstruction and increased airway hyper responsiveness leads to symptoms of wheeze, cough, chest tightness and difficulty in breathing. It affecting any age, race and socio-economic class globally and its prevalence is changing upwards worldwide. The increase in prevalence may be due to changes in lifestyle, rapid industrialization, tobacco, smoke, viral infections, chemical irritants and increase in air pollution. Siddha, an ancient system of Indian Medicine has recommended a number of drugs for indigenous plant sources for the treatment of Bronchial Asthma. One among them is Siddha polyherbal formulation Gowthamar chooranam. Aim: The aim of the present study was to identify the presence of bioactive phytocomponents in the Siddha polyherbal drug formulation Gowthamar chooranam by subjecting the drug to various studies like physicochemical analysis, phytochemical screening, and HPTLC. Methods: The ingredients present in the Siddha polyherbal formulation Gowthamar chooranam was first authenticated by the botanist and was purified. The purified ingredients of the drug was grounded to make a powdered form. The prepared siddha polyherbal formulation Gowthamar chooranam was sent it to the lab for the physiochemical analysis, phytochemical screening and HPTLC. The mentioned physicochemical and phytochemical analysis was conducted at The Tamil Nadu Dr. MGR Medical University, located at No.69, Anna Salai, Guindy, Chennai – 600 032. The HPTLC was carried out at Noble Research Solutions in Kolathur, Chennai – 600 099. Results: Physicochemical analysis of the study revealed 0.64% of loss on drying (LOD) at 1050C, 2.41% of total ash value, 0.8394% of acid insoluble ash, 1.65% of water soluble ash, 62.30% of water soluble extraction, 11.25% of Alcohol soluble extractive. Phytochemical screening showed the presence of bioactive compounds such as carbohydrates, saponin, phenols, tannin, flavonoids, diterpenes and Gum and mucilage. Seven distinct peaks are seen in the sample’s HPTLC finger printing examination, which indicates that it contains seven different phytocomponents. The highest Rf value of the peaks varies from 0.05 to 0.75. Conclusion: The findings aid in determining the formulations of siddha polyherbal drug Gowthamar chooranam and it reveals the presence of physicochemical and phytochemical properties of the drug which ensures the safety and therapeutic potential in the management of Swasakaasam (Bronchial Asthma) The study drug can also be used as a reference norms for the medicine of standard pharmaceutical product and further quality control enquires. This study provides the evidence for future clinical studies.

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Standardization of Vellarugu Chooranam: A Siddha Herbal Drug

Cited by 2 publications

References 4 publications

Standardization of a Siddha Poly Herbal Formulation Adhathodai Chooranam

Standardization of a Siddha Poly Herbal Formulation Adhathodai Chooranam

Standardization of Gowthamar chooranam – A Polyherbal Siddha Formulations in the Management of Swasakasam (Bronchial Asthma)

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