Standardized comparison of glucose intolerance in west African-origin populations of rural and urban Cameroon, Jamaica, and Caribbean migrants to Britain.

Mbanya, Jean Claude; Cruickshank, J.; Forrester, Terrence; Balkau, Beverley; Ngogang, Jeanne; Riste, Lisa; Forhan, Anne; Anderson, N. M.; Bennett, Franklyn I.; Wilks, RJ

doi:10.2337/diacare.22.3.434

Cited by 100 publications

(107 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The high prevalence of diabetes (16%) in this study reflects trends in sub‐Saharan Africa, where urban residence is associated with a 2‐ to 5‐fold higher risk of impaired glucose tolerance 58, 59. Oza‐Frank and Narayan60 reported that, compared with other immigrants in the United States, African men ranked second (7.8%) in prevalence of diabetes, and African women ranked third (4.6%).…”

Section: Discussionmentioning

confidence: 58%

Sex Differences in Cardiovascular Disease Risk of Ghanaian‐ and Nigerian‐Born West African Immigrants in the United States: The Afro‐Cardiac Study

Commodore-Mensah

Hill

Allen

et al. 2016

JAHA

View full text Add to dashboard Cite

BackgroundThe number of African immigrants in the United States grew 40‐fold between 1960 and 2007, from 35 355 to 1.4 million, with a large majority from West Africa. This study sought to examine the prevalence of cardiovascular disease (CVD) risk factors and global CVD risk and to identify independent predictors of increased CVD risk among West African immigrants in the United States.Methods and ResultsThis cross‐sectional study assessed West African (Ghanaian and Nigerian) immigrants aged 35–74 years in the Baltimore–Washington metropolitan area. The mean age of participants was 49.5±9.2 years, and 58% were female. The majority (95%) had ≥1 of the 6 CVD risk factors. Smoking was least prevalent, and overweight or obesity was most prevalent, with 88% having a body mass index (in kg/m2) ≥25; 16% had a prior diagnosis of diabetes or had fasting blood glucose levels ≥126 mg/dL. In addition, 44% were physically inactive. Among women, employment and health insurance were associated with odds of 0.09 (95% CI 0.033–0.29) and 0.25 (95% CI 0.09–0.67), respectively, of having a Pooled Cohort Equations estimate ≥7.5% in the multivariable logistic regression analysis. Among men, higher social support was associated with 0.90 (95% CI 0.83–0.98) lower odds of having ≥3 CVD risk factors but not with having a Pooled Cohort Equations estimate ≥7.5%.ConclusionsThe prevalence of CVD risk factors among West African immigrants was particularly high. Being employed and having health insurance were associated with lower CVD risk in women, but only higher social support was associated with lower CVD risk in men.

show abstract

Section: Discussionmentioning

confidence: 58%

Sex Differences in Cardiovascular Disease Risk of Ghanaian‐ and Nigerian‐Born West African Immigrants in the United States: The Afro‐Cardiac Study

Commodore-Mensah

Hill

Allen

et al. 2016

JAHA

View full text Add to dashboard Cite

show abstract

“…High prevalence of obesity in women surpassed the levels reported in other developing countries in Latin America (Martorell et al, 2000) and Africa (Martorell et al, 2000;Mokhtar et al, 2001). Of interest, in our international study (Mbanya et al, 1999;Cruickshank et al, 2001), 35% of Afro-Caribbean women in Britain were obese, as were 37% of women in Pomerleau et al's (1999) study. The alarming level of obesity among women is of public health significance and a challenge to scarce resources.…”

Section: Discussionmentioning

confidence: 66%

Social and dietary determinants of body mass index of adult Jamaicans of African origin

et al. 2003

Self Cite

View full text Add to dashboard Cite

Objectives: To determine the relationships between body mass index (BMI) and diet, social and behavioural factors among adult Jamaicans of African origin. Design: Cross-sectional. Setting: Urban communities in Jamaica, West Indies. Subjects: Three-hundred and sixty-three males and 561 females of African origin, aged 25 -74 y. Results: Women had higher mean BMIs (27.5 AE 6.4 kg=m 2 ) than men (23.4 AE 4.3 kg=m 2 ); 30.7% of women compared with 6.7% of men were obese. There was a tendency for obese men to have higher percentage of intakes from fat and less from carbohydrate, and women reported diets in which the percentage contribution of protein increased significantly with increasing BMI. In multivariate analyses, BMI was not explained by energy but was associated with protein intakes in females only. Predictors of relative weight were inversely related. Social (marital status) and behavioural (cigarette smoking) factors predicted BMI in both genders; older age in men and increased fibre intakes in women were associated with lower BMI. Conclusions: Social and behavioural factors are important determinants of body weight. Further investigations are needed which consider factors such as physical activity, genetic and other environmental variables as predictors of relative weight.

show abstract

“…Fieldworker procedures were rigorously standardised, a process repeated within teams every month, with regular cross-site visits every 4 months. Standardised measures of anthropometry such as BMI and WHR were taken by trained fieldworkers, after subjects had responded to a detailed lifestyle questionnaire [1].…”

Section: Baseline Examinationmentioning

confidence: 99%

“…Differences in disease rates between migrant and nonmigrant populations may supply important clues to the aetiology and hence the mechanism of disease [1]. For any ethnic group, lifestyle has a profound effect on insulin metabolism and on the incidence of type 2 diabetes and cardiovascular disease [2].…”

Section: Introductionmentioning

confidence: 99%

Marked differences in the IGF system that are associated with migration in comparable populations of Gujaratis living in Sandwell, UK, and Gujarat, India

et al. 2005

View full text Add to dashboard Cite

Aims/hypotheses: We previously reported independent links between the IGF system and the development of impaired glucose tolerance and cardiovascular risk. This study tests the hypothesis that the lifestyle change which accompanies population migration, with attendant increases in cardiovascular risk, is reflected by changes in the IGF system. Materials and methods: We compared a specific Gujarati community in Sandwell, UK (n=205), with people still resident in the same villages of origin near Navsari, India (n=246). We performed anthropometry and measured fasting plasma insulin, IGF-I, insulin-like growth factor binding protein (IGFBP)-1 and IGFBP-3. Results: Daily calorie intake, BMI and WHR were significantly higher in UK Gujaratis than in Indian Gujaratis. IGFBP-1 was significantly lower in UK migrants (mean 29.5 [95% CI 25.9-33.0] vs 56.5 [50.6-62.5]μg/l; F=48.4, p<0.001). Conversely, fasting insulin, IGFBP-3 and IGF-I were all higher in UK Gujaratis (mean IGF-I 145.9 [138.1-153.6]ng/ml in UK Gujaratis and 100.9 [94.6-107.3] ng/ml in Navsari Gujaratis; F=76.6, p<0.001). These differences were still apparent when adjustment was made for BMI by location for IGF-I (F=57.4, p<0.001) and IGFBP-3 (F=5.7, p=0.02), but were no longer apparent for IGFBP-1 and insulin. At the population level, the decrease in IGFBP-1 for a given increase in insulin was significantly smaller in UK Gujaratis, suggesting greater hepatic insulin resistance in this group. Conclusions/interpretation: Environmental factors have profound effects on circulating IGF system components and on the relationship between IGFBP-1, IGF-I and related metabolic variables. This may have long-term implications for the development of worsening glucose tolerance and cardiovascular disease.

show abstract

Standardized comparison of glucose intolerance in west African-origin populations of rural and urban Cameroon, Jamaica, and Caribbean migrants to Britain.

Abstract: The transition in glucose intolerance from Cameroon to Jamaica and Britain suggests that environment determines diabetes prevalence in these populations of similar genetic origin.

Cited by 100 publications

References 5 publications

Sex Differences in Cardiovascular Disease Risk of Ghanaian‐ and Nigerian‐Born West African Immigrants in the United States: The Afro‐Cardiac Study

Sex Differences in Cardiovascular Disease Risk of Ghanaian‐ and Nigerian‐Born West African Immigrants in the United States: The Afro‐Cardiac Study

Social and dietary determinants of body mass index of adult Jamaicans of African origin

Marked differences in the IGF system that are associated with migration in comparable populations of Gujaratis living in Sandwell, UK, and Gujarat, India

Contact Info

Product

Resources

About