Standardized Magnetic Resonance Imaging Reporting Using the Prostate Cancer Radiological Estimation of Change in Sequential Evaluation Criteria and Magnetic Resonance Imaging/Transrectal Ultrasound Fusion with Transperineal Saturation Biopsy to Select Men on Active Surveillance

Dieffenbacher, Svenja; Nyarangi‐Dix, Joanne; Giganti, Francesco; Bonekamp, David; Kesch, Claudia; Müller-Wolf, Maya B.; Schütz, Viktoria; Gasch, Claudia; Hatiboglu, Gencay; Hauffe, Marcus; Stenzinger, Albrecht; Duensing, Stefan; Schlemmer, Heinz–Peter; Moore, Caroline M.; Hohenfellner, Markus; Radtke, Jan Philipp

doi:10.1016/j.euf.2019.03.001

Cited by 37 publications

(25 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This variation in AS practice has been reflected in a recent consensus statement by the Prostate Cancer UK Expert Reference Group on AS, which reported significant variation in contemporary international guidelines, and in international and British practice [24]. There have been previous attempts, such as the PRECISE recommendation, to standardise mp-MRI reporting during AS based on consensus opinions [25][26][27][28]. However, the findings in this review would suggest up-take of these standards to be limited.…”

Section: Discussionmentioning

confidence: 92%

Can the Use of Serial Multiparametric Magnetic Resonance Imaging During Active Surveillance of Prostate Cancer Avoid the Need for Prostate Biopsies?—A Systematic Diagnostic Test Accuracy Review

Hettiarachchi

Geraghty

Rice

et al. 2021

European Urology Oncology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 92%

Can the Use of Serial Multiparametric Magnetic Resonance Imaging During Active Surveillance of Prostate Cancer Avoid the Need for Prostate Biopsies?—A Systematic Diagnostic Test Accuracy Review

Hettiarachchi

Geraghty

Rice

et al. 2021

European Urology Oncology

View full text Add to dashboard Cite

“…With the recently developed Prostate Cancer Radiological Estimation of Change in Sequential Evaluation (PRECISE) scoring system including only subjective criteria for the assessment of radiological progression of the disease 73 , 74 , the use of delta-radiomics in follow-up mpMRI scans could complement the developed baseline predictive model by acting as a quantitative tool for dynamic re-evaluation of the risk of PCa progression, further increasing confidence in mpMRI as an alternative to repeat biopsies. In this study, we already used PRECISE 5 as an alternative to histopathological progression of the disease, which aligns with the global trend towards heavier reliance on MRI in navigating follow-up in AS and makes the results more applicable to the routine clinical practice where the two surrogates are used interchangeably 52 , 75 – 77 .…”

Section: Discussionmentioning

confidence: 98%

MRI-derived radiomics model for baseline prediction of prostate cancer progression on active surveillance

Sushentsev

Rundo

Blyuss

et al. 2021

Sci Rep

View full text Add to dashboard Cite

Nearly half of patients with prostate cancer (PCa) harbour low- or intermediate-risk disease considered suitable for active surveillance (AS). However, up to 44% of patients discontinue AS within the first five years, highlighting the unmet clinical need for robust baseline risk-stratification tools that enable timely and accurate prediction of tumour progression. In this proof-of-concept study, we sought to investigate the added value of MRI-derived radiomic features to standard-of-care clinical parameters for improving baseline prediction of PCa progression in AS patients. Tumour T2-weighted imaging (T2WI) and apparent diffusion coefficient radiomic features were extracted, with rigorous calibration and pre-processing methods applied to select the most robust features for predictive modelling. Following leave-one-out cross-validation, the addition of T2WI-derived radiomic features to clinical variables alone improved the area under the ROC curve for predicting progression from 0.61 (95% confidence interval [CI] 0.481–0.743) to 0.75 (95% CI 0.64–0.86). These exploratory findings demonstrate the potential benefit of MRI-derived radiomics to add incremental benefit to clinical data only models in the baseline prediction of PCa progression on AS, paving the way for future multicentre studies validating the proposed model and evaluating its impact on clinical outcomes.

show abstract

“…At UCL, three different scanners were used: two 1.5-T (Symphony or Avanto, Siemens) and one 3-T system (Achieva, Philips), with a pelvic phased-array coil. At La Sapienza, all exams were performed on a 3-T scanner (Discovery MR750, GE Healthcare) using a 32-multichannel surface phased-array body coil, but in some of the earlier scans, an endorectal coil was also used UCL University College London study by Dieffenbacher and colleagues [8] reports that patients with a PRECISE score ≥ 3 on follow-up should be rebiopsied. Moreover, the concept of 'radiological progression' is not well-defined, as there are yet no volume or diameter thresholds that allow us to reliably distinguish between expected interscan variability (which can be considerable [21]) and true progression.…”

Section: Discussionmentioning

confidence: 99%

“…the PRECISE criteria could allow patients with MR stability to safely avoid biopsy). The discrimination between the absence and presence of AS disqualification using a PRECISE score was demonstrated with a ROC curve of 0.83 [8].…”

Section: Introductionmentioning

confidence: 99%

Interobserver reproducibility of the PRECISE scoring system for prostate MRI on active surveillance: results from a two-centre pilot study

et al. 2019

Self Cite

View full text Add to dashboard Cite

Objectives We aimed to determine the interobserver reproducibility of the Prostate Cancer Radiological Estimation of Change in Sequential Evaluation (PRECISE) criteria for magnetic resonance imaging in patients on active surveillance (AS) for prostate cancer (PCa) at two different academic centres. Methods The PRECISE criteria score the likelihood of clinically significant change over time. The system is a 1-to-5 scale, where 1 or 2 implies regression of a previously visible lesion, 3 denotes stability and 4 or 5 indicates radiological progression. A retrospective analysis of 80 patients (40 from each centre) on AS with a biopsyconfirmed low-or intermediate-risk PCa (i.e. ≤ Gleason 3 + 4 and prostate-specific antigen ≤ 20 ng/ml) and ≥ 2 prostate MR scans was performed. Two blinded radiologists reported all scans independently and scored the likelihood of radiological change (PRECISE score) from the second scan onwards. Cohen's κ coefficients and percent agreement were computed. Results Agreement was substantial both at a per-patient and a per-scan level (κ = 0.71 and 0.61; percent agreement = 79% and 81%, respectively) for each PRECISE score. The agreement was superior (κ = 0.83 and 0.67; percent agreement = 90% and 91%, respectively) when the PRECISE scores were grouped according to the absence/presence of radiological progression (PRECISE 1-3 vs 4-5). Higher inter-reader agreement was observed for the scans performed at University College London (UCL) (κ = 0.81 vs 0.55 on a per-patient level and κ = 0.70 vs 0.48 on a per-scan level, respectively). The discrepancies between institutions were less evident for percent agreement (80% vs 78% and 86% vs 75%, respectively). Conclusions Expert radiologists achieved substantial reproducibility for the PRECISE scoring system, especially when data were pooled together according to the absence/presence of radiological progression (PRECISE 1-3 vs 4-5).

show abstract

Standardized Magnetic Resonance Imaging Reporting Using the Prostate Cancer Radiological Estimation of Change in Sequential Evaluation Criteria and Magnetic Resonance Imaging/Transrectal Ultrasound Fusion with Transperineal Saturation Biopsy to Select Men on Active Surveillance

Cited by 37 publications

References 35 publications

Can the Use of Serial Multiparametric Magnetic Resonance Imaging During Active Surveillance of Prostate Cancer Avoid the Need for Prostate Biopsies?—A Systematic Diagnostic Test Accuracy Review

Can the Use of Serial Multiparametric Magnetic Resonance Imaging During Active Surveillance of Prostate Cancer Avoid the Need for Prostate Biopsies?—A Systematic Diagnostic Test Accuracy Review

MRI-derived radiomics model for baseline prediction of prostate cancer progression on active surveillance

Interobserver reproducibility of the PRECISE scoring system for prostate MRI on active surveillance: results from a two-centre pilot study

Contact Info

Product

Resources

About