“…Because of excellent tolerance of percutaneous thermal therapy, identifying an absolute contraindication for lung thermal ablation is difficult, with the exception of patients with untreatable coagulopathies . However, caution should be exercised for patients with: (i) poorly controlled infection or inflammation around the lesions, puncture site infection, or ulceration; (ii) severe bleeding tendency, platelets <50 × 10 9 /L, or severely disordered coagulation, in whom anticoagulation and/or antiplatelet drugs should be discontinued at least five to seven days before percutaneous ablation; (iii) ipsilateral pleural malignant effusions that are not well controlled; (iv) severe liver, kidney, heart, lung or brain function insufficiency, severe anemia, severe dehydration and nutritional and metabolic disorders that cannot be corrected or improved in the short term, severe systemic infections, high fever (>38.5°C); or (v) Eastern Cooperative Oncology Group (ECOG) score > 3.…”