Standing surface acoustic waves, and the mechanics of acoustic tweezer manipulation of eukaryotic cells

Bisymmetric coherent acoustic tweezers based on modulation of surface acoustic waves for dynamic and reconfigurable cluster manipulation of particles and cells

“…63 Therefore cell patterning to arrange cells in desired geometries has become an increasingly important tool in biotechnology because of its broad range of applications, especially in the field of tissue engineering and fundamental studies of cell biology. Cell manipulation needs to protect the cells from potential injury when they are exposed to external forces and energy fields, 64,65 as cells' functionalities and viability are essential for further biochemical studies. Compared with electrical, optical, and magnetic tweezers, numerous studies have demonstrated that acoustic tweezers are contactless and non-invasive to biological samples even after processing for hours.…”

Analysis of Acousto-Optic Phenomenon in SAW Acoustofluidic Chip and Its Application in Light Refocusing

“…In recent years, SAW devices have been further applied to the field of acoustofluidics [ 5 , 6 ]. Based on microelectromechanical systems (MEMS) technology, SAW acoustofluidic devices can realize precise operation [ 7 ] on droplets, particles, and cells [ 8 , 9 , 10 , 11 , 12 , 13 , 14 ] in a noninvasive, label-free, and contactless manner, making it a powerful and advanced tool in fields such as biology [ 15 ], chemistry [ 16 ], and forensic analysis [ 17 ].…”

Collapse pressure measurement of single hollow glass microsphere using single-beam acoustic tweezer

“…This nN-scale trapping force ensures stable trapping even at high pressure levels within the range of a few MPa and is robust against external forces. There are many types of acoustic tweezers, including approaches based on the use of surface acoustic [65] , [66] or traveling waves [67] and potential wells [68] . Of these, single-beam acoustic tweezers (SBATs) [58] , [62] , [63] , [64] , [69] , [70] , [71] can trap particles using a single transducer, enabling the selective trapping of either single or multiple particles depending on the particle size and beamwidth.…”