Staphylococcal Bacteraemia

Changes in incidence and aetiology of bacteraemia arising in hospital practice.

“…Many authors, including Hassall and Rountree (1959) and Faber et al (1960), have observed marked increases in staphylococcal bacteraemia. In this hospital staphylococcal bacteraemia has increased from 0.5/1,000 admissions in 1958 to 0.86/1,000 in 1965 ; the increase was confined to hospital-infected cases.…”

“…Emphasis has been placed on a marked rise in staphylococcal and Gram-negative bacteraemia, with a concomitant fall in potentially fatal infections due to the pneumococcus and Streptococcus pyogenes (Finland et al, 1959 ;Rogers, 1959;Faber et al, 1960). Factors other than antibiotics are involved in these changes; McHenry et al (1962a) listed the ageing population, the widespread use of precipitating surgical and instrumental procedures, the prolongation of life in seriously ill patients with limited ability to resist infection, and the use of immune-suppressing drugs as factors in the increase of Gram-negative bacteraemia.…”

Staphylococcal Septicaemia in a General Hospital

“…aureuis and Gram-negative bacilli. Faber et al (1960) also described a significant recent increase. The present series does seem to indicate a rising annual incidence in one hospital, resulting from a greater number of hospital infections.…”

Existing data sources for clinical epidemiology: The North Denmark Bacteremia Research Database

“…Studies of bacteremia have a longstanding tradition 5,6. In particular, Streptococcus pneumoniae ,7 Staphylococcus aureus ,8,9 and enteric Gram-negative rods10–12 have been studied extensively. In the 1970s and early 1980s, a number of thorough clinic-based outcome studies were conducted5,13,14 and two of the most influential papers on bacteremia were published by Weinstein et al in 1983 15,16.…”