Staphylococcus hominis native mitral valve bacterial endocarditis (SBE) in a patient with hypertrophic obstructive cardiomyopathy

Cunha, Burke A.; Esrick, Michael D.; LaRusso, Melissa

doi:10.1016/j.hrtlng.2006.11.002

Cited by 17 publications

(5 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…S. hominis can cause nosocomial bloodstream infections [10]–[12] and other opportunistic infections of humans [13], [14]. An increasing proportion of blood culture isolates of S. hominis that were atypical or misidentified as Staphylococcus equorum , led to the the formal description in 1998 of two S. hominis subspecies, including S. hominis subsp.…”

Section: Introductionmentioning

confidence: 99%

Multilocus Sequence Typing and Further Genetic Characterization of the Enigmatic Pathogen, Staphylococcus hominis

et al. 2013

View full text Add to dashboard Cite

Staphylococcus hominis is a commensal resident of human skin and an opportunistic pathogen. The species is subdivided into two subspecies, S. hominis subsp. hominis and S. hominis subsp. novobiosepticus, which are difficult to distinguish. To investigate the evolution and epidemiology of S. hominis, a total of 108 isolates collected from 10 countries over 40 years were characterized by classical phenotypic methods and genetic methods. One nonsynonymous mutation in gyrB, scored with a novel SNP typing assay, had a perfect association with the novobiocin-resistant phenotype. A multilocus sequence typing (MLST) scheme was developed from six housekeeping gene fragments, and revealed relatively high levels of genetic diversity and a significant impact of recombination on S. hominis population structure. Among the 40 sequence types (STs) identified by MLST, three STs (ST2, ST16 and ST23) were S. hominis subsp. novobiosepticus, and they distinguished between isolates from different outbreaks, whereas 37 other STs were S. hominis subsp. hominis, one of which was widely disseminated (ST1). A modified PCR assay was developed to detect the presence of ccrAB4 from the SCCmec genetic element. S. hominis subsp. novobiosepticus isolates were oxacillin-resistant and carriers of specific components of SCCmec (mecA class A, ccrAB3, ccrAB4, ccrC), whereas S. hominis subsp. hominis included both oxacillin-sensitive and -resistant isolates and a more diverse array of SCCmec components. Surprisingly, phylogenetic analyses indicated that S. hominis subsp. novobiosepticus may be a polyphyletic and, hence, artificial taxon. In summary, these results revealed the genetic diversity of S. hominis, the identities of outbreak-causing clones, and the evolutionary relationships between subspecies and clones. The pathogenic lifestyle attributed to S. hominis subsp. novobiosepticus may have originated on more than one occasion.

show abstract

Section: Introductionmentioning

confidence: 99%

Multilocus Sequence Typing and Further Genetic Characterization of the Enigmatic Pathogen, Staphylococcus hominis

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Though the microorganism isolated from his initial blood culture, Staphylococcus hominis, has been shown as a potential cause of IE, it is not considered a typical causative agent and thus satisfies minor rather than major criteria for diagnosis. 9 The broader class of coagulase-negative Staphylococcus organisms are however becoming a more common cause of IE. It should also be noted that right-sided endocarditis as in this case is more difficult to diagnose by blood culture because the organisms tend to be filtered in the lungs.…”

Section: Discussionmentioning

confidence: 99%

Percutaneous Removal of a Cardiac Mass in a Patient with Infective Endocarditis: A Case Report

Koney

Benmessaoud

Cole

et al. 2018

J Pediatr Intensive Care

View full text Add to dashboard Cite

Infective endocarditis (IE) in the pediatric population is uncommon and presents with nonspecific signs. Nonetheless, prompt diagnosis and management are critical given its high mortality rate. We present the case of a 15-year-old boy who initially presented with bilateral multifocal pneumonia and was found to have IE with a right ventricular vegetation. The vegetation was removed percutaneously, obviating a more invasive surgical approach. The patient tolerated the procedure well and rapidly improved following removal of the vegetation. This case report highlights the utility of a novel, minimally invasive approach for the management of cardiac masses.

show abstract

“…Staphylococcus hominis is the third most commonly isolated species among CoNS from clinical cases ( 3 ). S. hominis is the major pathogen causing bacteremia, septicemia, endophthalmitis, and endocarditis ( 4 , 5 ). Furthermore, this organism has been reported to exhibit resistance to the most frequently used antimicrobials such as macrolides, lincosamides, vancomycin, and streptogramins ( 6 , 7 ).…”

Section: Genome Announcementmentioning

confidence: 99%

Draft Genome Sequence of Staphylococcus hominis BHG17 Isolated from Wild Bar-Headed Goose ( Anser indicus ) Feces

et al. 2017

View full text Add to dashboard Cite

show abstract

Staphylococcus hominis native mitral valve bacterial endocarditis (SBE) in a patient with hypertrophic obstructive cardiomyopathy

Cited by 17 publications

References 12 publications

Multilocus Sequence Typing and Further Genetic Characterization of the Enigmatic Pathogen, Staphylococcus hominis

Multilocus Sequence Typing and Further Genetic Characterization of the Enigmatic Pathogen, Staphylococcus hominis

Percutaneous Removal of a Cardiac Mass in a Patient with Infective Endocarditis: A Case Report

Draft Genome Sequence of Staphylococcus hominis BHG17 Isolated from Wild Bar-Headed Goose ( Anser indicus ) Feces

Contact Info

Product

Resources

About