State-Dependent Cross-Brain Information Flow in Borderline Personality Disorder

Abstract

This study provides a neural correlate for a core diagnostic and clinical feature of BPD. Results indicate that hyperscanning may deliver state-associated biomarkers for clinical social neuroscience. In addition, at least some neural deficits of BPD may be more reversible than is currently assumed for personality disorders.

Two-Person Approaches to Studying Social Interaction in Psychiatry: Uses and Clinical Relevance

“…Related studies have revealed that interpersonal brain synchrony reflects social dysfunctions and intervention effects to some extent (80,83). Thus, it could be possible to improve the social communication and interpersonal relationships of patients with psychiatric disorders by manipulating interpersonal brain synchrony.…”

Getting into sync: Data‐driven analyses reveal patterns of neural coupling that distinguish among different social exchanges

“…Within the temporo-parietal junction (TPJ), for example, brain responses become synchronized and/or contingent between interactants during economic exchanges (Jahng, Kralik, Hwang, & Jeong, 2017;Tang et al, 2016;Zhang, Liu, Pelowski, Jia, & Yu, 2017), verbal and non-verbal communication (Bilek et al, 2015(Bilek et al, , 2017Kinreich, Djalovski, Kraus, Louzoun, & Feldman, 2017;Rojiani, Zhang, Noah, & Hirsch, 2018;Wilson, Molnar-Szakacs, & Iacoboni, 2008), and cooperative joint-action tasks (Abe et al, 2019). Within the temporo-parietal junction (TPJ), for example, brain responses become synchronized and/or contingent between interactants during economic exchanges (Jahng, Kralik, Hwang, & Jeong, 2017;Tang et al, 2016;Zhang, Liu, Pelowski, Jia, & Yu, 2017), verbal and non-verbal communication (Bilek et al, 2015(Bilek et al, , 2017Kinreich, Djalovski, Kraus, Louzoun, & Feldman, 2017;Rojiani, Zhang, Noah, & Hirsch, 2018;Wilson, Molnar-Szakacs, & Iacoboni, 2008), and cooperative joint-action tasks (Abe et al, 2019).…”

“…Interestingly, brain regions implicated in social cognitive processes feature frequently in patterns of neural coupling across various types of social interaction, presumably reflecting the mutual recruitment of mechanisms that permit the transmission and encoding of social information. Within the temporo-parietal junction (TPJ), for example, brain responses become synchronized and/or contingent between interactants during economic exchanges (Jahng, Kralik, Hwang, & Jeong, 2017;Tang et al, 2016;Zhang, Liu, Pelowski, Jia, & Yu, 2017), verbal and non-verbal communication (Bilek et al, 2015(Bilek et al, , 2017Kinreich, Djalovski, Kraus, Louzoun, & Feldman, 2017;Rojiani, Zhang, Noah, & Hirsch, 2018;Wilson, Molnar-Szakacs, & Iacoboni, 2008), and cooperative joint-action tasks (Abe et al, 2019). This is perhaps unsurprising given the putative role of the TPJ in inferring the intentional and motivational states of others (Bardi, Six, & Brass, 2017;Carlson, Koenig, & Harms, 2013;Eddy, 2016;Frith & Frith, 2006), a process that is essential for interacting successfully with others.…”

“…By evaluating dual-fMRI data in a model-free, hypothesis-free manner, whereby no a priori assumptions are made, these techniques are more appropriate for the nonlinear, unpredictable dynamic of naturalistic social exchange (Nastase, Gazzola, & Keysers, 2019). Recently, Bilek et al (2015Bilek et al ( , 2017 demonstrated how two such data-driven techniques can be combined to investigate neural coupling during social interaction. With groupindependent component analysis (gICA), one can extract spatiotemporal patterns of brain responses from a set of continuous recordings acquired from multiple interacting dyads.…”

Commentary: Using second-person neuroscience to elucidate the mechanisms of reciprocal social interaction

“…Finally, both frameworks highlight the potential important theoretical and clinical implications of studying social cognition within interactive brains, especially with regards to clinical populations (Schilbach, 2016;Bilek et al, 2017). By doing so, both serve to encourage and stimulate a new line of research.…”