State-of-the-art cerium nanoparticles as promising agents against human viral infections

Zandi, Milad; Hosseini, Fatemeh; Adli, Ahmad Hosseinzadeh; Salmanzadeh, Shokrollah; Behboudi, Emad; Halvaei, Peyman; Khosravi, Ayda; Abbasi, Saeed

doi:10.1016/j.biopha.2022.113868

Cited by 10 publications

(3 citation statements)

References 70 publications

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“…The glycans are also essential for ACE2-virus surface interaction. They influence the conformation of the ACE2 receptor to allow the interaction of spike with ACE2 [ 28 ]. The glycans can modulate Spike-ACE2 interactions by masking polypeptide epitopes [ 29 ].…”

Section: Sars-cov-2 Spike Glycoprotein and Mutations Affecting Its Bi...mentioning

confidence: 99%

SARS-CoV-2 mechanisms of cell tropism in various organs considering host factors

Behboudi,

Nooreddin Faraji,

Daryabor

et al. 2024

Heliyon

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Section: Sars-cov-2 Spike Glycoprotein and Mutations Affecting Its Bi...mentioning

confidence: 99%

SARS-CoV-2 mechanisms of cell tropism in various organs considering host factors

Behboudi,

Nooreddin Faraji,

Daryabor

et al. 2024

Heliyon

Self Cite

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“…The influenza strains are chosen in accordance with the WHO and European Medicines Agency's yearly guidelines. [82] All age ranges can get the influenza vaccination Inflexal® V without a problem. [83,84] InfectoVac® Flu, Isiflu® V, and Viroflu® are additional trade names for Inflexal®V that are used in Germany, Italy, as well as the United Kingdom, respectively [85][86][87].…”

Section: Inflexal®vmentioning

confidence: 99%

Virosome: A vector in vaccine delivery

Karpe,

Gupta,

Vyas

et al. 2024

BIO Web Conf.

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These days vaccines are considered the best economical and effective technique for preventing and handling bacterial infections, like human papillomavirus (HPV) or meningitis, allergies, autoimmune Relevant Disorders, Microbial Infections, and many more viral diseases. Annually millions of lives are saved from death-causing infections and other relevant disorders with the help of proper immunization with the help of vaccines. But still, many diseases are not yet preventable by vaccines and there is a chance of the improvement of current vaccines with help of many approaches. One of these is a compound known as a virosome, which is produced when pure haemagglutinin and neuraminidase projections of the influenza virus surface are removed from viral envelope and deposited on the exterior of unilamellar liposomes.Studies have shown that in order to attain the desired therapeutic effect, a physical attachment between the target antigen and the virosomal carrier is necessary. A virosome can bind to and “infect” host cells and deliver the antigen directly into the processing pathway which is an Alternatively, the virosome may be phagocytosed by an APC. So Our review gives a novel idea of the vector technology for vaccine delivery, its properties, method of preparation, and importance as well as some applications of different virosomal vaccine discoveries.

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“…Meanwhile, cerium nanoparticles exhibit anti-inflammatory properties and effectively mitigate the autoimmune response ( Nosrati et al, 2023 ). Moreover, the enhanced photocatalytic and antibacterial activities make them particularly promising for anti-viral applications ( Naidi et al, 2021 ; Zandi et al, 2022 ).…”

Section: Introductionmentioning

confidence: 99%

Polylactic acid electrospun membrane loaded with cerium nitrogen co-doped titanium dioxide for visible light-triggered antibacterial photocatalytic therapy

Lv,

Xia,

Sun

et al. 2024

Front. Microbiol.

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Wound infection caused by multidrug-resistant bacteria poses a serious threat to antibiotic therapy. Therefore, it is of vital importance to find new methods and modes for antibacterial therapy. The cerium nitrogen co-doped titanium dioxide nanoparticles (N-TiO2, 0.05Ce-N-TiO2, 0.1Ce-N-TiO2, and 0.2Ce-N-TiO2) were synthesized using the hydrothermal method in this study. Subsequently, electrospinning was employed to fabricate polylactic acid (PLA) electrospun membranes loaded with the above-mentioned nanoparticles (PLA-N, PLA-0.05, PLA-0.1, and PLA-0.2). The results indicated that cerium and nitrogen co-doping tetrabutyl titanate enhanced the visible light photocatalytic efficiency of TiO2 nanoparticles and enabled the conversion of ultraviolet light into harmless visible light. The photocatalytic reaction under visible light irradiation induced the generation of ROS, which could effectively inhibit the bacterial growth. The antibacterial assay showed that it was effective in eliminating S. aureus and E. coli and the survival rates of two types of bacteria under 30 min of irradiation were significantly below 20% in the PLA-0.2 experimental group. Moreover, the bactericidal membranes also have excellent biocompatibility performance. This bio-friendly and biodegradable membrane may be applied to skin trauma and infection in future to curb drug-resistant bacteria and provide more alternative options for antimicrobial therapy.

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State-of-the-art cerium nanoparticles as promising agents against human viral infections

Cited by 10 publications

References 70 publications

SARS-CoV-2 mechanisms of cell tropism in various organs considering host factors

SARS-CoV-2 mechanisms of cell tropism in various organs considering host factors

Virosome: A vector in vaccine delivery

Polylactic acid electrospun membrane loaded with cerium nitrogen co-doped titanium dioxide for visible light-triggered antibacterial photocatalytic therapy

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