State of the Art for Metastatic Histologies

Haghshenas, Varan; Sayari, Arash J.; Shehabeldin, Ahmed; Marco, Rex A.W.

doi:10.1007/978-3-030-50722-0_14

Cited by 1 publication

(2 citation statements)

References 130 publications

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“…Lymphomas, for example, typically do not induce extensive bony destruction like most solid tumor metastases and even multiple myeloma might, but diagnosis typically still hinges on biopsy. 14 In cases of metastatic sarcoma to the spine, prognosis varies widely. For example, soft-tissue sarcomas that metastasize to the spine confer a poor prognosis, with a survival rate of approximately 5 months (with the exception of myxoid liposarcoma, where survival is more than 80% at 5 years and more than 70% at 10 years).…”

Section: Workup Of the New Spinal Lesionmentioning

confidence: 99%

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Spinal Tumors: Diagnosis and Treatment

Goodwin

Buchowski

Schwab

et al. 2022

J Am Acad Orthop Surg

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Tumors that present in or around the spine can be challenging to diagnose and treat. A proper workup involves a complete history and physical examination, appropriate staging studies, appropriate imaging of the entire spine, and a tissue biopsy. The biopsy defines the lesion and guides treatment, but in some rare instances, rapid neurological decline may lead to urgent or emergent surgery before it can be analyzed. “Enneking-appropriate” margins should remain the goal for primary tumors while adequate debulking/separation/stabilization are often the goals in metastatic disease. Primary tumors of the spine are rare and often complex tumors to operate on—achieving Enneking-appropriate margins provides the greatest chance of survival while decreasing the chance of local recurrence. Metastatic tumors of the spine are increasingly more common, and timing of surgery must be considered within the greater framework of the patient and the patient's disease, deficits, stability, and other treatments available. The specific tumor type will dictate what other multidisciplinary approaches are available, allowing for chemotherapy and radiation as needed.

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Section: Workup Of the New Spinal Lesionmentioning

confidence: 99%

“…For example, soft-tissue sarcomas that metastasize to the spine confer a poor prognosis, with a survival rate of approximately 5 months (with the exception of myxoid liposarcoma, where survival is more than 80% at 5 years and more than 70% at 10 years). 14…”

Section: Workup Of the New Spinal Lesionmentioning

confidence: 99%