State-of-the-art of polymer/fullerene nanocomposites in biomedical field

Buzea, Cristina; Pacheco, Ivan

doi:10.1016/b978-0-323-99515-3.00010-9

Cited by 1 publication

(2 citation statements)

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“…The presence of C 60 molecules leads to an increase in the photoconductivity of conducting polymers and organo-metallic compounds [7]. Due to their spherical form and unique electron properties, fullerenes attract researchers in the fields of medicine and biology [8][9][10][11]. Nanomaterials based on C 60 have good prospects in cancer therapy [12][13][14].…”

Section: Introductionmentioning

confidence: 99%

“…Supramolecular chemistry approaches for the preparation of host–guest inclusion complexes with fullerenes have made significant progress over the past decade [ 3 ]. Polymer-fullerene nanocomposites are new materials with many applications in the biomedical field [ 8 ]. Fullerenes can be retained in the cavity of host polymer molecules due to van der Waals and hydrophobic interactions and π-π stacking, as well as electrostatic interactions [ 52 ].…”

Section: Introductionmentioning

confidence: 99%

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Hydrophilization and Functionalization of Fullerene C60 with Maleic Acid Copolymers by Forming a Non-Covalent Complex

Samoilova,

Krayukhina,

Klemenkova

et al. 2024

Polymers

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In this study, we report an easy approach for the production of aqueous dispersions of C60 fullerene with good stability. Maleic acid copolymers, poly(styrene-alt-maleic acid) (SM), poly(N-vinyl-2-pyrrolidone-alt-maleic acid) (VM) and poly(ethylene-alt-maleic acid) (EM) were used to stabilize C60 fullerene molecules in an aqueous environment by forming non-covalent complexes. Polymer conjugates were prepared by mixing a solution of fullerene in N-methylpyrrolidone (NMP) with an aqueous solution of the copolymer, followed by exhaustive dialysis against water. The molar ratios of maleic acid residues in the copolymer and C60 were 5/1 for SM and VM and 10/1 for EM. The volume ratio of NMP and water used was 1:1.2–1.6. Water-soluble complexes (composites) dried lyophilically retained solubility in NMP and water but were practically insoluble in non-polar solvents. The optical and physical properties of the preparations were characterized by UV-Vis spectroscopy, FTIR, DLS, TGA and XPS. The average diameter of the composites in water was 120–200 nm, and the ξ-potential ranged from −16 to −20 mV. The bactericidal properties of the obtained nanostructures were studied. Toxic reagents and time-consuming procedures were not used in the preparation of water-soluble C60 nanocomposites stabilized by the proposed copolymers.

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