“…For instance, longitudinal studies in pediatric cancer patients have shown that 15-25 years after initial cancer diagnosis, there is an 8.2-fold higher rate of cardiac death compared with age-and sex-matched national averages [2•]. There are three principal causes for this association: (1) cancer and CVD share many similar risk factors such as smoking, obesity, and advanced age; [3,4] (2) given the overall improved survival of patients undergoing cancer therapy as noted above, de novo CVD develops as a normal process in this aging population; and (3) cancer therapies including radiation, traditional chemotherapies, and newer novel targeted therapies can cause significant cardiovascular complications. These complications include heart failure, myocardial ischemia, arrhythmias, valvular heart disease, thromboembolism, hypertension, pulmonary hypertension, and pericardial diseases [3,5].…”