This paper presents exact solutions for the nonlinear bending problem, the buckling loads, and postbuckling configurations of a perfect and an imperfect bioinspired helicoidal composite beam with a linear rotation angle. The beam is embedded on an elastic medium, which is modeled by two elastic foundation parameters. The nonlinear integro-differential governing equation of the system is derived based on the Euler–Bernoulli beam hypothesis, von Kármán nonlinear strain, and initial curvature. The Laplace transform and its inversion are directly applied to solve the nonlinear integro-differential governing equations. The nonlinear bending deflections under point and uniform loads are derived. Closed-form formulas of critical buckling loads, as well as nonlinear postbuckling responses of perfect and imperfect beams are deduced in detail. The proposed model is validated with previous works. In the numerical results section, the effects of the rotation angle, amplitude of initial imperfection, elastic foundation constants, and boundary conditions on the nonlinear bending, critical buckling loads, and postbuckling configurations are discussed. The proposed model can be utilized in the analysis of bio-inspired beam structures that are used in many energy-absorption applications.