Certain polymers can be excited by electric, chemical, pneumatic, optical, or magnetic field to change their shape or size. For convenience and practical actuation, using electrical excitation is the most attractive stimulation method and the related materials are known as electroactive polymers (EAP) and artificial muscles. One of the attractive applications that are considered for EAP materials is biologically inspired capabilities, i.e., biomimetics, and successes have been reported that previously were considered science fiction concepts. Today, there are many known EAP materials. Some of the EAP materials also exhibit the reverse effect of converting mechanical strain to electrical signal allowing using them as sensors and energy harvesters. Efforts are made worldwide to turn EAP materials to actuators-of-choice and they involve developing their scientific and engineering foundations including the understanding of their operation principles. These are also involve developing effective computational chemistry models, comprehensive material science, and electro-mechanics analytical tools. These efforts have been leading to better understanding the parameters that control their capability and durability. Moreover, effective processing techniques are developed for their fabrication, shaping, electroding, and characterization. While progress have been reported in the research and development of all the types of EAP materials, the trend in recent years has been growing towards significant development in using dielectric elastomers.These characteristics are making them highly attractive for use in muscle-like actuators. Some are biologically inspired (i.e., biomimetic applications) [8,9,11], and all can function without hard metallic gears and mechanisms. Examples of the applications of EAP actuators include a polypyrrole fish [71], ionic polymer-metal composite robot fish [23], miniature dielectric elastomer grippers for satellites [5], ionic conductor loudspeakers [51], an electrostrictive polymer catheter [35], a haptic interface [32], active braille displays [9], a fish-like blimp [45], static electric rotary motors [3], worm-like robots [46], a crawling robot with no hard electronics [42], facial animatronic devices [11], optical devices [107], biomedical devices, microfluidic devices, and even a wearable device to assist eyelid blinking [103]. The impressive improvements in the field [52,68] are increasingly attracting the interest of engineers and scientists from many different disciplines.Many EAP actuators are still emerging and need further advancement in order for them to form part of mass-produced products. This requires the use of computational chemistry models, comprehensive material science, electro-mechanic analytical tools, and material processing research. To maximize their actuation capability and durability, effective fabrication, shaping, and electroding techniques are being developed. In addition, techniques of characterizing their response as well as documenting them in databases and related ...