Static magnetic field attenuates lipopolysaccharide-induced multiple organ failure: A histopathologic study in mice

Lai, Wei Yi; Huang, Yun-Ju; Chang, Wei Jen; Wang, Hsin-Ta; Fong, Tsorng Harn; Lin, Che Tong; Huang, Haw Ming

doi:10.3109/09553002.2015.959669

International Journal of Radiation Biology

2015

DOI: 10.3109/09553002.2015.959669

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Static magnetic field attenuates lipopolysaccharide-induced multiple organ failure: A histopathologic study in mice

Wei Yi Lai¹,

Yun-Ju Huang²,

Wei Jen Chang³

et al.

Abstract: SMF show potential as a viable prophylactic alternative for controlling LPS-induced MOF.

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Cited by 2 publications

References 39 publications

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Using a static magnetic field to attenuate the severity in COVID-19-invaded lungs

Lai,

Fan,

Lee

et al. 2024

Sci Rep

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Two important factors affecting the progress of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are the S-protein binding function of ACE2 receptors and the membrane fluidity of host cells. This study aimed to evaluate the effect of static magnetic field (SMF) on S-protein/ACE2 binding and cellular membrane fluidity of lung cells, and was performed in vitro using a Calu-3 cell model and in vivo using an animal model. The ability of ACE2 receptors to bind to SARS-CoV-2 spike protein on host cell surfaces under SMF stimulation was evaluated using fluorescence images. Host lung cell membrane fluidity was tested using fluorescence polarization to determine the effects of SMF. Our results indicate that 0.4 T SMF can affect binding between S-protein and ACE2 receptors and increase Calu-3 cell membrane fluidity, and that SMF exposure attenuates LPS-induced alveolar wall thickening in mice. These results may be of value for developing future non-contact, non-invasive, and low side-effect treatments to reduce disease severity in COVID-19-invaded lungs.

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Using a static magnetic field to attenuate the severity in COVID-19-invaded lungs

Lai,

Fan,

Lee

et al. 2024

Sci Rep

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Enhancement of natural killer cell cytotoxicity by using static magnetic field to increase their viability

Lin

Feng

et al. 2019

Electromagnetic Biology and Medicine

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Static magnetic field attenuates lipopolysaccharide-induced multiple organ failure: A histopathologic study in mice

Abstract: SMF show potential as a viable prophylactic alternative for controlling LPS-induced MOF.

Cited by 2 publications

References 39 publications

Using a static magnetic field to attenuate the severity in COVID-19-invaded lungs

Using a static magnetic field to attenuate the severity in COVID-19-invaded lungs

Enhancement of natural killer cell cytotoxicity by using static magnetic field to increase their viability

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