Static magnetic fields decrease nocturnal pineal cAMP in the rat

Decreased plasma levels of nitric oxide metabolites, angiotensin II, and aldosterone in spontaneously hypertensive rats exposed to 5 mT static magnetic field

“…There is substantial and growing evidence that static magnetic fields (SMF) less than 1 tesla (T) can influence physiological processes in vivo: pain [Takeshige and Sato, 1996;Vallbona et al, 1997;Holcomb et al, 2000;Brown et al, 2002;Hinman, 2002;Weintraub et al, 2003], bone repair and formation [Bruce et al, 1987;Mevissen et al, 1994;Darendeliler et al, 1997;Yan et al, 1998;Xu et al, 2001], inflammation and wound healing [Lud and Demeckiy, 1990;Weinberger et al, 1996;Man et al, 1999;Alfano et al, 2001;Segal et al, 2001;Rogachefsky et al, 2004], anticonvulsant effects [McLean et al, 2003], enhanced chemotherapy [Gray et al, 2000], spatial discrimination learning [Levine and Bluni, 1994], melatonin reduction [Welker et al, 1983;Olcese et al, 1985;Olcese and Reuss, 1986;Stehle et al, 1988], cyclic AMP reduction [Rudolph et al, 1988], central nervous system function [Rosen and Lubowsky, 1987;Veliks et al, 2004], action potential generation [Lohmann et al, 1991;Popescu and Willows, 1999;Wang et al, 2003Wang et al, , 2004, enhanced tumor apoptosis [Tofani et al, 2001[Tofani et al, , 2002, and increased c-fos gene expression [Němec et al, 2001]. Therefore, characterizing the physiological transduction mechanism of SMF on BP in both hypertension and hypotension, remains an important area of research toward the development of better p...…”

II. Therapeutic Effects of Alternating Current Pulsed Electromagnetic Fields in Multiple Sclerosis

“…(Bawin and Adey, 1976;Blackman et al, 1982; Geomagnetic perturbations influence bird be- Rusovan and Kanje, 1992a;JoUey et al, 1983;havior (Ossenkopp and Barbieto, 1978) and in Karabakhtsian et al, 1994;Trabulsi et al, 1996). humans, changes in geomagnetic activity affect Some of the most important calcium-related several physiological and behavioral measures processes such as synaptic neurotransmitter (Subramanyam et al, 1985;Persinger, 1988) and synthesis and release and levels of cAMP, eshave also been associated with the increased in-sential for the functioning of the neuron cidence of epileptic seizures and admissions to (Matthews and Gersdorff, 1996), are influenced psychiatric hospitals (Friedman et al, 1963;by EMFs (Kaczmarek and Adey, 1974;Rosen Venkatraman, 1976;Rajaram and Mitra, 1981;and Lubowsky, 1987;Rudolph et al, 1988;Keshavan et al, 1981). Rosen, 1992).…”

Demyelination as An Epiphenomenon in Multiple Sclerosis

“…Finally, external application of picoTesla range MF, which has been shown to rapidly inhibit melatonin secretion (Welker et al, 1983;Rudolph et al, 1988;Semm, 1992), was reported in a small number of patients to be beneficial in the symptomatic treatment of MS press u; b; Sandyk & Iacono, in press). Most remarkably, improvement in symptoms occurred shortly after termination of treatment which lasted from 10 to 20 minutes.…”