“…We therefore model a dendrite-soma system as two interconnected integrate-and-fire units, a system studied in the context of connected pairs of neurons [26,27]. To model dendrite-soma systems, we consider that each compartment has independent intrinsic noise, a distinct refractory period, and common stimulation of intensity s. These effects are distinct from dendritic N-methyl D-Aspartate (NMDA) spikes [25,[28][29][30][31][32], calcium spikes [21,22,33], or other simplified models of dendritic activity lacking either a back-propagating action potential or a clear refractory period [34,35].…”