Statistical Study on Malignant Melanoma in Japan (1970-1976)

Ohsumi, Takeshi; Seiji, Makoto

doi:10.1620/tjem.121.355

Cited by 24 publications

(8 citation statements)

References 3 publications

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“…However, the incidence of malignant melanoma arising from mucosal membrane is relatively high in Japan compared with Western countries. Regarding the head-and-neck region, it constitutes approximately 30% of all malignant melanomas in Japan, whereas it represents only 1% in Western countries (4,5). Thus, the rate of patients with mucosal malignant melanoma of the head and neck in both Japan and the United States comes to approximately 0.1 per 100,000, suggesting that this specific condition may generally be rare worldwide (6).…”

Section: Introductionmentioning

confidence: 99%

Mucosal Malignant Melanoma of the Head and Neck Treated by Carbon Ion Radiotherapy

Yanagi¹,

Mizoe²,

Hasegawa³

et al. 2009

International Journal of Radiation Oncology*Biology*Physics

117

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Section: Introductionmentioning

confidence: 99%

Mucosal Malignant Melanoma of the Head and Neck Treated by Carbon Ion Radiotherapy

Yanagi¹,

Mizoe²,

Hasegawa³

et al. 2009

International Journal of Radiation Oncology*Biology*Physics

117

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“…2) Wilson and Moran reported only 8 proven cases of primary malignant melanoma of the lung in the Pulmonary Tumor Registry of the Armed Forces Institute of Pathology, accounting for 0.01% of all lung tumors, 3) and the incidence of primary lung malignant melanoma is approximately 0.4% of all malignant melanomas. 4) It is difficult to distinguish primary malignant melanoma of the lung from metastatic melanoma. The diagnostic criteria for primary malignant melanoma of the lung based on pathological findings include (1) a junctional change with a "dropping off" or "nesting" of malignant cells containing melanin just beneath the bronchial epithelium, (2) invasion of the bronchial epithelium by melanoma cells in an area where the bronchial epithelium is damaged, and (3) an obvious melanoma beneath an epithelium with these changes.…”

Section: Discussionmentioning

confidence: 99%

A Resected Melanoma of the Lung Metastasized from an Occult Skin Lesion: A Case Report

Shimmyo

Ando

Kurimoto

et al. 2014

ATCS

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An 86-year-old woman with a history of right breast cancer resected seven years ago had a small pulmonary nodule located in left S5. Diagnosis was made by bronchoscopy using the endobronchial ultrasonography-guided sheath (EBUS-GS) method, but a histological diagnosis was not obtained. Wedge resection was performed due to suspicion of a metastatic lesion from breast cancer based on radiological findings. The tumor was subsequently found to be malignant melanoma of the lung. An initial diagnosis of primary melanoma of the lung was made because a melanoma lesion at another site was not seen despite a detailed work up. However, 8 months after surgery, a malignant melanoma appeared at the tip of the right index finger. We rediagnosed the lung lesion as a metastatic malignant melanoma based on the low incidence of primary melanoma of the lung and on the pathological features.

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“…Mucosal malignant melanoma is more common in Japan than in other countries, but tumors of the vulvovaginal region are very rare (1,2). Women with vaginal melanoma have been reported to have an average survival of only 19 months (3).…”

Section: Discussionmentioning

confidence: 99%

A Case of Pedunculated Malignant Melanoma of the Vaginal Mucosa

Kimura

Furuya

2001

The Journal of Dermatology

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We report an 84-year-old Japanese woman who presented with a pedunculated malignant melanoma of the vaginal mucosa. Mucosal melanoma is believed to be more common in Japan than other countries, but such tumors of the vulvovaginal region are quite unusual. In our patient, three tumors were connected by a narrow pedicle. Three black tumors measuring 5-10 mm in diameter with a common pedicle were seen on the vaginal mucosa at five o'clock from the cervix. The tumors were hanging from the narrow pedicle. On histologic examination, they were diagnosed as malignant melanoma. Resection was done with a distal margin of 3 cm from the tumors and a margin of 1 cm from the cervix. The patient has had no evidence of local recurrence or distant metastasis. In our patient, the three main tumors had a common pedicle, which seems to be a unique finding. Since pedunculated malignant melanomas are rare, making a clinical diagnosis is difficult. Although pedunculated melanomas are recognized as having a high malignant potential because these lesions are generally thick, a relatively good outcome is sometimes reported. In our patient, there was no tumor infiltration into the dermis of the pedicle, and this may be one reason for the good outcome at present. There has been no previous report of a mucosal melanoma consisting of three tumors like those in the present patient.

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Statistical Study on Malignant Melanoma in Japan (1970-1976)

Cited by 24 publications

References 3 publications

Mucosal Malignant Melanoma of the Head and Neck Treated by Carbon Ion Radiotherapy

Mucosal Malignant Melanoma of the Head and Neck Treated by Carbon Ion Radiotherapy

A Resected Melanoma of the Lung Metastasized from an Occult Skin Lesion: A Case Report

A Case of Pedunculated Malignant Melanoma of the Vaginal Mucosa

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