The emergence of the COVID-19 pandemic in late 2019 led to a global crisis of unprecedented scale and complexity that disrupted almost every aspect of human life. The pandemic has taken people, institutions and governments by surprise, so the impact of the virus has been profound and far-reaching. The rapid and relentless spread of the pandemic has challenged global health systems, strained economies, altered daily routines in educational settings and at work, and tested the resilience of communities worldwide. Different studies have identified vulnerabilities in the world’s ability to respond to health emergencies at the individual and societal levels. This study presents a systematic literature review and theoretical analysis of the disruptions caused by COVID-19 to help formulate strategies that encourage flexibility and resilience in the face of such complex and interconnected disruptions. The article analyzes the consequences of the COVID-19 pandemic through the prism of two main theories: the theory of situational crisis communications (type of crisis, its history, responsibility, perceived seriousness, predictable probability, crisis communications strategies, post-crisis reputation), as well as the theory of social learning (learning through observation, modeling and imitation, positive and negative reinforcement in the formation of behavior). In addition, the nature of society’s adaptation to the challenges of the COVID-19 pandemic is also considered through the prism of the theory of subversive innovations (progress in communication technologies, new methods of remote work and education, the entry of social networks into the business world, the introduction of asynchronous communication). The article summarizes the scientific progress on the following main consequences of the COVID-19 pandemic in the workplace, healthcare system, and education. The study provides recommendations on the steps that individuals, institutions and governments can take to increase readiness and ability to adapt to the next crisis (interdisciplinary cooperation, analysis of communication strategies, system analysis). The analysis conducted in the article also made it possible to outline the most promising directions for further qualitative intervention studies (in-depth case studies taking into account the specific context of regions, organizations or communities to identify effective and ineffective policies and practices; qualitative interviews with key stakeholders to understand the intricacies of decision-making in the context of the pandemic crisis); qualitative action studies (building community resilience, collaborative research efforts involving policymakers, health experts and community representatives to develop crisis response policies jointly) and quantitative studies (analysis of pandemic spread, impact of vaccination on disease control, analysis of the economic effects of the pandemic, etc.).