Stearic acid is well absorbed from short- and long-acyl-chain triacylglycerol in an acute test meal

Abstract

Objective: Absorption of stearic acid from natural oils has been shown to be efficient, but it is claimed to be lower from shortand long-acyl-chain triacylyglycerol molecules (Salatrim). The aim was to measure the apparent absorption of stearic acid from Salatrim fat in an acute test meal. Design: Double-blind crossover study. Subjects: Ten healthy male volunteers, of whom eight completed the study. Methods: The subjects were studied on two occasions after consumption of a single high-fat meal either without (control) or with 30 g of Salatrim. Fecal samples were collected for 96 h after the meal and the fat was extracted for analysis of the content and composition of free and esterified long-chain fatty acids. Results: Baseline fecal fat was 5.672.6 g/day increasing to 10.474.9 g/day after addition of Salatrim (P ¼ 0.001). During the whole collection period, the baseline fecal free and esterified fatty acids were 2.672.3 and 0.870.7 g, respectively. After Salatrim meal the corresponding figures increased to 5.973.6 g (P ¼ 0.001) and 1.5 (71.2) g (P ¼ 0.003), respectively. The total fecal stearic acid after control meal was 0.9770.9 g. Consumption of Salatrim with 16.770.5 g of stearic acid increased the content to 3.1271.6 g (Po0.001), with apparent absorption of 87%. Conclusions: The apparent absorption of stearic acid does not differ from its absorption from natural fats. The status of Salatrim as a low-energy fat substitute needs to be re-evaluated. Sponsorship: University of Turku.

Influence of different dietary oil consumption on nutrient malabsorption: An animal trial using Sprague Dawley rats

“…The intestine hold extremely high efficiency to take up dietary lipids, and over 95% of the ingested dietary oils and fats could be absorbed under the normal physiological conditions (Lairon, 2009). Study showed that the intestinal absorption of stearic acid from natural oils and fats was between 86% and 98%, although this was also affected by their positional distribution within the TAG molecules in the dietary lipids (Tuomasjukka et al, 2007). The intestinal absorption capability of different fatty acids was different, which were resulted from the differences of acid transporters affinity toward different fatty acids (Nassir & Abumrad, 2009).…”

“…Studies showed that the fecal composition could reflect the comprehensive contributions of the bile acid, gut microbiota, and intestinal cell sloughing, and the previous study also investigated the differences of the intestine absorption toward dietary lipids or structured lipids by characterizing the fecal fatty acid profiles (Shang et al, 2017). It was suggested that the fecal fatty acid profiles could be used to quantify the intestinal absorption efficiency of the dietary lipids (Tuomasjukka et al, 2007).…”