Stem Cell Research and Health Education

Eve, David J.; Marty, Phillip J.; McDermott, Robert J.; Klasko, Stephen K.; Sanberg, Paul R.

doi:10.1080/19325037.2008.10599033

Cited by 12 publications

(6 citation statements)

References 119 publications

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“…Cells generate offspring, which can be formed into specialized cells or stem cells. 5 Stem cells maintain their population themselves, the division of each of them leads to the addition of another stem cell, and their number will remain stagnant if the symmetrical division is taking place. Stem cell inhabitants are present in fewer numbers in the whole body and they are undifferentiated moreover they don't have focused functions when they have given rise.…”

Section: Embryonic Stem Cells (Esm)mentioning

confidence: 99%

Role of Stem Cells in the Management of Type-I Diabetes Mellitus

Arjun HR,

Halagali,

Tausi

et al. 2023

Ind. J. Pharm. Edu. Res

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The paper aims to accent Type-1 DM along with its etiology, pathophysiology, and treatment in this review. Diabetes is considered the chronic ailment of hypoglycemia ensuing from the duo of the dearth of insulin action and secretion of insulin considered as both. Moreover, Type-1 is a result of autoimmune of the cells of islets of the pancreas. The confrontation to the insulin or secretion of insulin lacking due to changes in living standards, habit change, dearth of exercise along with aging also, but one of the most relevant and prevalent reasons is a lifestyle change and also change in food habits along with the stress of the day-to-day life. Stem cell therapy is an expensive treatment and obtaining stem cells also is difficult due to ethical issues and availability is also less. Presently accessible ailment for type-1 is insulin supply therapy but it is also associated with many hitches. Advanced replacements like islets have demonstrated fruitful results in reinstating glucose levels. Moreover, in severe type 1-DMM and it has been delimited due to its high cost, not economic process, shortfall of donors, etc. Replacement of beta-like cells that are obtained from differentiation of human Pluripotent Stem Cells (hPSCs) also exhibited results with flying colors and gained the spotlight, but in stem cell therapy getting beta cells along with complete insulin secretion is decisive.

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Section: Embryonic Stem Cells (Esm)mentioning

confidence: 99%

Role of Stem Cells in the Management of Type-I Diabetes Mellitus

Arjun HR,

Halagali,

Tausi

et al. 2023

Ind. J. Pharm. Edu. Res

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“…Institutional strategy, envisioned as a science-driven practice advancement priority, is executed through a discovery–translation–application mandate, deployed across medical, surgical, radiological, and laboratory medicine specialties. 1,19…”

Section: Preparing the Next-generation Physicianmentioning

confidence: 99%

Regenerative medicine curriculum for next-generation physicians

et al. 2019

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Regenerative sciences are poised to transform clinical practice. The quest for regenerative solutions has, however, exposed a major gap in current healthcare education. A call for evidence-based adoption has underscored the necessity to establish rigorous regenerative medicine educational programs early in training. Here, we present a patient-centric regenerative medicine curriculum embedded into medical school core learning. Launched as a dedicated portal of new knowledge, learner proficiency was instilled by means of a discovery–translation–application blueprint. Using the “from the patient to the patient” paradigm, student experience recognized unmet patient needs, evolving regenerative technologies, and ensuing patient management solutions. Targeted on the deployment of a regenerative model of care, complementary subject matter included ethics, regulatory affairs, quality control, supply chain, and biobusiness. Completion of learning objectives was monitored by online tests, group teaching, simulated clinical examinations along with longitudinal continuity across medical school training and residency. Success was documented by increased awareness and proficiency in domain-relevant content, as well as specialty identification through practice exposure, research engagement, clinical acumen, and education-driven practice advancement. Early incorporation into mainstream medical education offers a tool to train next-generation healthcare providers equipped to adopt and deliver validated regenerative medicine solutions.

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“…The restrictive nature of the US legislation meant that a number of state and alternative sources (from Federal) for funding of ESC research arose. This varied from state to state dependent on their own legislation and a review, published in 2008, provided a summary of the availability of funding across the states (48). The legislation has changed since then, as in 2009 the restrictive use of ESCs was moderated in the US and it will be interesting to see whether this will influence the type of cells studied.…”

Section: Stem Cell Publications In Cell Transplantation Between 2008 mentioning

confidence: 99%

Stem Cell Research in Cell Transplantation: Sources, Geopolitical Influence, and Transplantation

et al. 2010

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If the rapidly progressing field of stem cell research reaches its full potential, successful treatments and enhanced understanding of many diseases are the likely results. However, the full potential of stem cell science will only be reached if all possible avenues can be explored and on a worldwide scale. Until 2009, the US had a highly restrictive policy on obtaining cells from human embryos and fetal tissue, a policy that pushed research toward the use of adult-derived cells. Currently, US policy is still in flux, and retrospective analysis does show the US lagging behind the rest of the world in the proportional increase in embryonic/ fetal stem cell research. The majority of US studies being on either a limited number of cell lines, or on cells derived elsewhere (or funded by other sources than Federal) rather than on freshly isolated embryonic or fetal material. Neural, mesenchymal, and the mixed stem cell mononuclear fraction are the most commonly investigated types, which can generally be classified as adult-derived stem cells, although roughly half of the neural stem cells are fetal derived. Other types, such as embryonic and fat-derived stem cells, are increasing in their prominence, suggesting that new types of stem cells are still being pursued. Sixty percent of the reported stem cell studies involved transplantation, of which over three quarters were allogeneic transplants. A high proportion of the cardiovascular systems articles were on allogeneic transplants in a number of different species, including several autologous studies. A number of pharmaceutical grade stem cell products have also recently been tested and reported on. Stem cell research shows considerable promise for the treatment of a number of disorders, some of which have entered clinical trials; over the next few years it will be interesting to see how these treatments progress in the clinic.

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Stem Cell Research and Health Education

Cited by 12 publications

References 119 publications

Role of Stem Cells in the Management of Type-I Diabetes Mellitus

Role of Stem Cells in the Management of Type-I Diabetes Mellitus

Regenerative medicine curriculum for next-generation physicians

Stem Cell Research in Cell Transplantation: Sources, Geopolitical Influence, and Transplantation

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