Stem Cell Transplantations in Patients with Malignant Lymphoma: Costs in a Dutch University Hospital in the Period 1984-1995

Groot, C.A. Uyl-de; Ossenkoppele, Gert J.; Buijt, I.; Huijgens, Peter C.

doi:10.1089/152581699319786

Cited by 4 publications

(1 citation statement)

References 17 publications

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“…The NST in collaboration with the transplant programme team can deal with the NS process, ensuring that the nutritional intervention becomes a truly integral part of supportive care for the patient [ 2 ]. However, HSCT patients are poorly compliant to all that is nutrition and NS [ 2 ], and the use of artificial nutritional interventions not only incur numerous side effects but also significantly affect costs [ 21 , 22 ]. These types of factors including others such as social, psychological, and ethical, can impact on decisions regarding NS provision.…”

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confidence: 99%

Nutritional support in patients undergoing haematopoietic stem cell transplantation: a multicentre survey of the Gruppo Italiano Trapianto Midollo Osseo (GITMO) transplant programmes

Botti¹,

Liptrott²,

Gargiulo³

et al. 2015

ecancer

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A survey within Italian haematopoietic stem cell transplant (HSCT) programmes was performed, in order to obtain a snapshot of nutritional support (NS) in patients undergoing HSCT. The primary objective was to verify whether an evidence-based practice (EBP) approach to NS was implemented in HSCT centres. A multicentre survey was performed by questionnaire, covering the main areas of NS (screening, treatment planning, monitoring, nutritional counselling, and methods of nutritional support). The results indicated a significant variation between clinical practice and evidence-based guidelines in terms of clinical pathways, decision-making, and care provision regarding NS. Further research is required to identify reasons for the limited application of EBP and measures that may be undertaken to address such issues. Development of a multidisciplinary educational programme in order to raise awareness of the issue should be undertaken.

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Section: Introductionmentioning

confidence: 99%

Nutritional support in patients undergoing haematopoietic stem cell transplantation: a multicentre survey of the Gruppo Italiano Trapianto Midollo Osseo (GITMO) transplant programmes

Botti¹,

Liptrott²,

Gargiulo³

et al. 2015

ecancer

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Costs of high-dose chemotherapy and peripheral blood progenitor cell autograft for breast cancer

Rosa

Lalle

Pandolfi

et al. 2001

Bone Marrow Transplant

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Summary:The aim of the study was to analyze the real cost of single or tandem high-dose chemotherapy (HDC) and peripheral blood progenitor cell autologous transplant (PBPCT) in patients with breast cancer. We analyzed the costs of 40 PBPCT performed in 20 patients. Tandem transplant was planned for each patient. Resources used and direct costs were identified for each patient. The study was carried out using the hospital perspective and monetary values were reported in 1999 Euro. The mean cost of whole procedure for single transplant was 20 816.63 Euro, while the mean cost of tandem transplant was 38 770.83 Euro. The cost distribution in the two groups was similar: the most expensive phase of procedure was the supportive phase post transplant (about 60% of total cost), with the categories of cost most represented being professional fees (about 28%) and pharmacy (about 35%). Awaiting more convincing trials of the clinical advantage of HDC in breast cancer, our analytical evaluation of transplant costs for different therapeutic options, single or tandem, permits identification of the most expensive categories in order to intervene for cost savings. Bone Marrow Transplantation (2001) 27, 1031-1035. Keywords: cost analysis; high-dose chemotherapy; peripheral blood progenitor cell autograft; breast cancer High-dose chemotherapy (HDC) and peripheral blood progenitor cell autologous transplant (PBPCT) have been extensively used in patients with breast cancer.1 Although trials evaluating the clinical benefit of this approach are under investigation, 2,3 the treatment costs restrict its use both on and off clinical trials. The knowledge of the cost distribution is important in reducing costs and in negotiating reimbursement strategies for individual institutions. [4][5][6] In this study we carried out a retrospective analysis of the costs of PBPCT in 20 patients with metastatic or highrisk breast cancer treated in an intensive care unit at an Italian hospital. The patients received double high-dose chemotherapy followed by PBPC support. The cost analysis was conducted using the hospital perspective. The aim of the study was to analyze the real cost of the procedure considering each intervention involved in order to identify which part of the procedure was most expensive and if there was the possibility for cost saving. Patients and methods PatientsForty consecutive PBPCT were performed in 20 patients with breast cancer. Tandem transplant was planned for each patient. Seven patients had metastatic disease and 13 had high-risk breast cancer with more than 10 positive nodes.All patients had received standard chemotherapy regimens before HDC including CEF (5-fluorouracil, cyclophosphamide and epirubicin) or docetaxel + epirubicin. Highrisk patients received HDC after four courses of standard chemotherapy. Metastatic breast cancer patients were treated with HDC only if in complete or partial response, receiving a median of two cycles after response.PBPC collections were performed after a standard cycle of chemotherapy followe...

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Allogeneic stem cell transplantation for the non-Hodgkin’s lymphomas and Hodgkin’s disease

Hale

Phillips

2000

Cancer Treatment Reviews

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Stem Cell Transplantations in Patients with Malignant Lymphoma: Costs in a Dutch University Hospital in the Period 1984-1995

Cited by 4 publications

References 17 publications

Nutritional support in patients undergoing haematopoietic stem cell transplantation: a multicentre survey of the Gruppo Italiano Trapianto Midollo Osseo (GITMO) transplant programmes

Nutritional support in patients undergoing haematopoietic stem cell transplantation: a multicentre survey of the Gruppo Italiano Trapianto Midollo Osseo (GITMO) transplant programmes

Costs of high-dose chemotherapy and peripheral blood progenitor cell autograft for breast cancer

Allogeneic stem cell transplantation for the non-Hodgkin’s lymphomas and Hodgkin’s disease

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