T he poultry industry represents a cornerstone in the Egyptian economy and a major source of animal protein production. It is associated with a large amount of national consumption that represents over 600 million dollars (FAO, 2013). Excessive usage of antibiotics in poultry has led to the emergence of highly resistant microbial path-ogens (Agyare et al., 2018). So, there is an urgent need to develop environmentally friendly materials and complementary treatments such as natural immune modifying cytokines (Umar et al., 2019).Improvement of meat and egg quality, and disease resistance to viral diseases as Newcastle disease in the Egyptian chicken traits with traditional breeding programs is