Stent for Life Initiative placed at the forefront in Egypt 2011

Sobhy, Mohamed; Sadaka, Mohamed; Okasha, Nireen; Farag, Elsayed; Saleh, Ayman; Ismail, Hussein; Seteiha, Mohamed El; Ragy, Hany; Hameed, Mohamed Abdel; Mehanna, Radwa A.

doi:10.4244/eijv8spa19

Cited by 9 publications

(4 citation statements)

References 15 publications

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“…These results were in accordance with Sobhy M et al who conducted a registry assessing the current situation of Egyptian patients with acute STEMI. The mean age in the registry was 56.01 ± 10.61 years [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

Primary PCI versus pharmacoinvasive strategy for ST elevation myocardial infarction

Helal

Shaheen

El-Hammady

et al. 2018

IJC Heart & Vasculature

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BackgroundThe rationale for pharmacoinvasive strategy is that many patients have a persistent reduction in flow in the infarct-related artery. The aim of the present study is to assess safety and efficacy of pharmacoinvasive strategy using streptokinase compared to primary PCI and ischemia driven PCI on degree of myocardial salvage and outcomes.Methods and resultsSixty patients with 1st attack of acute STEMI within 12 h were randomized to 4 groups: primary PCI for patients presented to PPCI-capable centers (group I), transfer to PCI if presented to non-PCI capable center (group II), pharmacoinvasive strategy “Streptokinase followed by PCI within 3–24 h” (group III) and fibrinolytic followed by ischemia driven PCI (group IV). The primary endpoint is the infarction size and microvascular obstruction (MVO) measured by cardiac MRI (CMR) 3–5 days post-MI. Pharmacoinvasive strategy led to a significant reduction in infarction size, MVO and major adverse cardiac and cerebrovascular event (MACCE) compared to group IV but minor bleeding was significantly higher compared to other groups.ConclusionsPharmacoinvasive strategy resulted in effective reperfusion and smaller infarction size in patients with early STEMI who could not undergo primary PCI within 2 h after the first medical contact. This can provide a wide time window for PCI when the application of primary PCI within the optimal time limit is not possible. However, it was associated with a slightly increased risk of minor bleeding.

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Section: Discussionmentioning

confidence: 99%

Primary PCI versus pharmacoinvasive strategy for ST elevation myocardial infarction

Helal

Shaheen

El-Hammady

et al. 2018

IJC Heart & Vasculature

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“…According to the stent for life protocol implemented at Assiut University Hospitals since October 2015, 7 all patients from Assiut governorate area with STEMI are subjected to P-PCI. Our hospital provides a round-the-clock service of P-PCI with 16 trained physicians and dedicated nurses.…”

Section: Methodsmentioning

confidence: 99%

Predictors of no-reflow in patients undergoing primary percutaneous coronary intervention. Thrombus aspiration was protective

Abolghasemi

Mohamed

et al. 2018

The Egyptian Heart Journal

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“…This was a prospective study which enrolled 238 consecutive patients with first acute STEMI who underwent PPCI in the period from October 2015 till September 2016. Patients were recruited from an ongoing registry (operational since October 2015), which evaluates the effects of a well-structured AMI care program (Stent For Life) on short-and long-term outcomes (Sobhy et al, 2012). Our center is a tertiary center providing a round-the-clock service of PPCI with highly experienced PCI physicians and dedicated nurses.…”

Section: Study Populationmentioning

confidence: 99%

Electrocardiographic measures of ventricular repolarization dispersion and arrhythmic outcomes among ST elevation myocardial infarction patients with pre‐infarction angina undergoing primary percutaneous coronary intervention

Ahmed¹,

Abdel‐Nazeer²,

Abolghasemi³

et al. 2019

Noninvasive Electrocardiol

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Background: Arrhythmias are considered one of the major causes of death in ST elevation myocardial infarction (STEMI), particularly in the early in-hospital phase. Preinfarction angina (PIA) has been suggested to have a protective role. Objectives:To study the difference in acute electrocardiographic findings between STEMI patients with and without PIA and to assess the in-hospital arrhythmias in both groups. Material and Methods: We prospectively enrolled 238 consecutive patients with STEMI. Patients were divided into two groups: those with or without PIA. ECG data recorded and analyzed included ST-segment resolution (STR) at 90 min, corrected QT interval (QTc) and dispersion (QTD), T-peak-to-T-end interval (Tp-Te), and dispersion and Tp-Te/QT ratio. In-hospital ventricular arrhythmias encountered in both groups were recorded. Predictors of in-hospital arrhythmias were assessed among different clinical and electrocardiographic parameters. Results: Of the 238 patients included, 42 (17%) had PIA and 196 (83%) had no PIA.Patients with PIA had higher rates of STR (p < 0.0001), while patients with no PIA had higher values of QTc (p = 0.006), QTD (p = 0.001), Tp-Te interval (p = 0.001), Tp-Te dispersion (p < 0.0001), and Tp-Te/QT ratio (p = 0.01) compared to those with angina preceding their incident infarction (PIA). This was reflected into significantly higher rates of in-hospital arrhythmias among patients with no PIA (20% vs. 7%, p = 0.04). Furthermore, longer Tp-Te interval and higher Tp-Te/QT ratio independently predicted in-hospital ventricular arrhythmias. Conclusion:Pre-infarction angina patients had better electrocardiographic measures of repolarization dispersion and encountered significantly less arrhythmic events compared to patients who did not experience PIA.

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Stent for Life Initiative placed at the forefront in Egypt 2011

Abstract: Despite the logistical difficulties, excellent outcomes for acute interventional reperfusion strategy in STEMI can be achieved in our country, possibly similar to those seen in the West. There is a strong need for making the practice of PCI in STEMI more widespread in developing regions.

Cited by 9 publications

References 15 publications

Primary PCI versus pharmacoinvasive strategy for ST elevation myocardial infarction

Primary PCI versus pharmacoinvasive strategy for ST elevation myocardial infarction

Predictors of no-reflow in patients undergoing primary percutaneous coronary intervention. Thrombus aspiration was protective

Electrocardiographic measures of ventricular repolarization dispersion and arrhythmic outcomes among ST elevation myocardial infarction patients with pre‐infarction angina undergoing primary percutaneous coronary intervention

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