Stent Placement Is Justifiable in End-Stage Patients with Malignant Airway Tumours

Sutedja, G.; Schramel, Franz M.N.H.; Kralingen, Klaas van; Postmus, Pieter E.

doi:10.1159/000196410

Cited by 21 publications

(7 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There is no clear advantage of any type of stent [88,89,91,92,95,[98][99][100][101][102][103][104]. Stents can be used temporarily [92,105] in a multimodality concept of cancer care and as a last palliative measure for end-stage cancer patients [106,107]. The efficacy regarding functional improvement and QoL appears to be proven [90,108].…”

Section: Clinical Experience and Resultsmentioning

confidence: 99%

Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents

Bolliger¹

2006

Eur Respir J

339

276

View full text Add to dashboard Cite

Minimally invasive diagnostic and therapeutic approaches in medicine have been applied for a more selective and tailored approach to reduce patients' morbidity and mortality. The efficacy of interventional pulmonology for palliation of patients with central airways obstruction has been established and its curative potential for intralesional treatment of early cancer has raised great interest in current screening programmes. This is due to the fact that surgical resection and systemic nodal dissection as the gold standard is relatively morbid and risky, especially when dealing with individuals with limited functional reserves due to smoking-related comorbidities, such as chronic obstructive pulmonary disease. Furthermore, such comorbidities have been proven to harbour early stage lesions of several millimetres in size without involvement of nodal disease that may be amenable to local bronchoscopic treatment.Therefore, the success of minimally invasive strategies for palliation and treatment with curative intent strongly depends on the diligent identification of the various factors in lung cancer management, including full comprehension of the limits and potential of each particular technique. Maximal preservation of quality of life is a prerequisite in successfully dealing with individuals at risk of harbouring asymptomatic early lung cancer, to prevent aggressive surgical diagnostic and therapeutic strategies since overdiagnosis remains an issue that is heavily debated.In the palliative setting of alleviating central airway obstruction, laser resection, electrocautery, argon plasma coagulation and stenting are techniques that can provide immediate relief, in contrast to cryotherapy, brachytherapy and photodynamic therapy with delayed effects. With curative intent, intraluminal techniques that easily coagulate early stage cancer lesions will increase the implementation of interventional pulmonology for benign and relatively benign diseases, as well as early cancer lesions and its precursors at their earliest stage of disease.

show abstract

Section: Clinical Experience and Resultsmentioning

confidence: 99%

Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents

Bolliger¹

2006

Eur Respir J

339

276

View full text Add to dashboard Cite

show abstract

“…All patients had preceding Nd-Yag laser treatment. 5 Furthermore, Reichle et al 6 in their prospective analysis showed efficacy of argon plasma coagulation (APC) in the treatment of malignant airway stenoses, with 67% achieving good result and complication rate of 3.5%.…”

Section: Discussionmentioning

confidence: 99%

Role of Palliative Tracheobronchial Stenting in Hospice Patients

Bandyopadhyay

Induru

2010

Am J Hosp Palliat Care

View full text Add to dashboard Cite

Lung cancer is the leading cause of cancer mortality and morbidity. Patients with advanced lung cancer have distressful symptoms like dyspnea. It has severe negative impact on the quality of life. Airway stenting has become widespread for palliation of airway stenosis in patients with metastatic airways disease. Although it provides improvement in symptoms, actual survival benefit is limited with severe potential complications. Appropriate patient selection in terms of site of tumor, type of stent placement is needed to achieve maximum benefit for patients. Here we will discuss 2 patients with advanced lung cancer who received bronchial stent for intractable dyspnea. Although there was dramatic improvement in symptoms and quality of life, both died shortly. Was there any benefit of stenting remained unanswered.

show abstract

“…They have been widely reported to result in improved symptom control and quality of life with an acceptable risk of peri‐procedural complications (bleeding, hypoxia, airway obstruction) of 3–17%, and procedure‐related mortality <1% 2,10,11,16–20 . Even in the setting of CAO associated with very advanced malignancy, patients at risk of imminent suffocation can benefit from emergency stenting 21,22 …”

Section: Approach To the Patientmentioning

confidence: 99%

Managing obstruction of the central airways

Williamson¹,

Phillips²,

Hillman³

et al. 2010

Internal Medicine Journal

View full text Add to dashboard Cite

Lung cancer is the most common cause of cancer death in Australia, Europe and the USA. Up to 20-30% of these cancers eventually affect the central airways and result in reduced quality of life, dyspnoea, haemoptysis, post-obstructive pneumonia and ultimately death. Non-malignant processes may also lead to central airway obstruction and can have similar symptoms. With the development of newer technologies, the last 20 years have seen the emergence of the field of interventional pulmonology to deal specifically with the diagnosis and management of thoracic malignancy, including obstruction of the central airways. This review discusses the pathology, pre-procedure work-up and management options for obstructing central airway lesions. Several treatment modalities exist for dealing with endobronchial pathology with local availability and expertise guiding choice of treatment. While the literature lacks large, multicentre, randomized studies defining the optimal management strategy for a given problem, there is growing evidence from numerous case studies of improved physiology, of quality of life and possibly of survival with modern interventional techniques.

show abstract

Stent Placement Is Justifiable in End-Stage Patients with Malignant Airway Tumours

Cited by 21 publications

References 11 publications

Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents

Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents

Role of Palliative Tracheobronchial Stenting in Hospice Patients

Managing obstruction of the central airways

Contact Info

Product

Resources

About