Stereoselective Preparation of Spiran‐Bridged, Sandwiched Bisarenes.

Abstract

2005 Cycloalkylphenyl derivatives Q 0760 Stereoselective Preparation of Spiran-Bridged, Sandwiched Bisarenes. -The synthesis of dioxospirans (III), (V), and (XVI) is presented. The former is prepared by a new synthetic route. The products are transformed into vinyl triflates which smoothly undergo Pd-catalyzed cross-coupling under Stille, Suzuki, or Negishi conditions to afford the title compounds. Hydrogenation of the unsaturated molecules proceeds with high stereoselectivity. -(ROLANDSGARD, M.; BALDAWI, S.; SIRBU, D.; BJOERNSTAD, V.; ROEMMING, C.; UNDHEIM*, K.; Tetrahedron 61 (2005) 16, 4129-4140; Dep. Chem., Univ. Oslo, N-0315 Oslo, Norway; Eng.) -Jannicke 34-126